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10/14/2025 7:42:38 AM | Browse: 9 | Download: 13
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 110503
Country China
Received
2025-06-09 08:35
Peer-Review Started
2025-06-09 08:35
To Make the First Decision
Return for Revision
2025-06-18 02:20
Revised
2025-07-02 15:20
Second Decision
2025-09-16 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-16 07:11
Articles in Press
2025-09-16 07:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-06 14:15
Publish the Manuscript Online
2025-10-14 07:42
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Sleep disorders in hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Jin Qian, Ming-Hao Ruan, Zhi-Jie Wang, Wei Dong, Jin-Yong Jia, Xiao-Chen Feng and Hui Liu
ORCID
Author(s) ORCID Number
Xiao-Chen Feng http://orcid.org/0000-0003-3204-3622
Hui Liu http://orcid.org/0000-0003-4599-5702
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82270634
Corresponding Author Hui Liu, MD, Professor, The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, No. 225 Changhai Road, Shanghai 200082, China. liuhuigg@hotmail.com
Key Words Sleep disorders; Circadian rhythm; Clock gene; Hepatocellular carcinoma; Risk factors; Prevention strategies
Core Tip Hepatocellular carcinoma (HCC) remains a globally prevalent malignancy, traditionally attributed to etiological factors such as viral hepatitis, alcohol-related liver disease, and metabolic dysfunction-associated fatty liver disease. Alarmingly, the global incidence of HCC continues to rise, with more than 900000 new cases reported in 2020, a trend not fully explained by these established risk factors. Emerging evidence highlights sleep disorders as a novel contributor to hepatocarcinogenesis. This review systematically explores the association between sleep disturbances and HCC pathogenesis, focusing on the underlying pathological mechanisms through which disrupted sleep patterns may drive HCC progression.
Publish Date 2025-10-14 07:42
Citation <p>Qian J, Ruan MH, Wang ZJ, Dong W, Jia JY, Feng XC, Liu H. Sleep disorders in hepatocellular carcinoma. <i>World J Gastrointest Oncol</i> 2025; 17(10): 110503</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i10/110503.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i10.110503
Full Article (PDF) WJGO-17-110503-with-cover.pdf
Manuscript File 110503_Auto_Edited_093857.docx
Answering Reviewers 110503-answering-reviewers.pdf
Audio Core Tip 110503-audio.mp3
Conflict-of-Interest Disclosure Form 110503-conflict-of-interest-statement.pdf
Copyright License Agreement 110503-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 110503-non-native-speakers.pdf
Peer-review Report 110503-peer-reviews.pdf
Scientific Misconduct Check 110503-scientific-misconduct-check.png
Scientific Editor Work List 110503-scientific-editor-work-list.pdf
CrossCheck Report 110503-crosscheck-report.pdf