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Articles Published Processes
10/14/2025 7:42:33 AM | Browse: 32 | Download: 164
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Received |
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2025-06-11 06:04 |
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Peer-Review Started |
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2025-06-11 06:04 |
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First Decision by Editorial Office Director |
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2025-07-15 06:29 |
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Return for Revision |
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2025-07-15 06:29 |
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Revised |
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2025-07-17 15:42 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-08-18 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-18 06:55 |
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Articles in Press |
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2025-08-18 06:55 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-09 00:09 |
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Publish the Manuscript Online |
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2025-10-14 07:42 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Contrast-enhanced ultrasound as a non-invasive diagnostic modality for pancreatic ductal adenocarcinoma: The question of Ki67 for study validation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Terence N Moyana |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Terence N Moyana, Division of Diagnostic and Molecular Pathology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa K1H 8L6, Ontario, Canada. tmoyana@toh.ca |
| Key Words |
Contrast-enhanced ultrasound; Quantitative parameters; Imaging modalities; Pancreatic ductal adenocarcinoma; Ki67 |
| Core Tip |
Correlations have been reported between contrast-enhanced ultrasound (CEUS) quantitative parameters and Ki67/tumor differentiation. However, the validation process is still a work in progress. Meticulous attention should be paid to subtypes of pancreatic ductal adenocarcinoma selected for testing, the suitability of Ki67 as the gold standard, the counting methodology and grade cut-offs. Overall, CEUS appears valuable in assessing pancreatic ductal adenocarcinoma. However, it should be regarded one more additional tool along with other imaging modalities such as computed tomography, magnetic resonance imaging and positron emission tomography scan. CEUS can also be augmented by endoscopic ultrasound-guided fine needle biopsy for tissue procurement. In certain situations, detective flow imaging endoscopic ultrasonography could be an alternative to CEUS. |
| Publish Date |
2025-10-14 07:42 |
| Citation |
Moyana TN. Contrast-enhanced ultrasound as a non-invasive diagnostic modality for pancreatic ductal adenocarcinoma: The question of Ki67 for study validation. World J Gastrointest Oncol 2025; 17(10): 110570 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i10/110570.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i10.110570 |
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