BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/18/2025 10:04:52 AM | Browse: 3 | Download: 0
 |
Received |
|
2025-06-13 09:17 |
|
Peer-Review Started |
|
2025-06-13 09:17 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-06-24 11:40 |
|
Revised |
|
2025-07-08 08:05 |
|
Second Decision |
|
2025-07-31 02:40 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-07-31 03:05 |
|
Articles in Press |
|
2025-07-31 03:05 |
|
Publication Fee Transferred |
|
2025-07-09 15:02 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-08-05 08:58 |
|
Publish the Manuscript Online |
|
2025-08-18 10:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Anesthesiology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Efficacy and safety of different doses of dexmedetomidine on gastrointestinal function recovery after laparoscopic colorectal surgery
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Chen, Wen-Lu Tang, Chun-Tian Li, Yu Zhao, Bing Li, Lian-Ming Liao, Tian-Hua Lin and Liang-Cheng Zhang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Fujian Province |
No. 2021J011438 |
|
| Corresponding Author |
Liang-Cheng Zhang, Department of Anaesthesiology, Fujian Medical University Union Hospital, No. 29 Xin-Quan Road, Fuzhou 350000, Fujian Province, China. zhanglc@fjmu.edu.cn |
| Key Words |
Dexmedetomidine; Laparoscopic colorectal surgery; Gastrointestinal function; Adverse event; Retrospective study |
| Core Tip |
Both low-dose and high-dose dexmedetomidine enhance gastrointestinal recovery after laparoscopic colorectal surgery, significantly shortening time to first flatus, defecation, and oral intake vs controls. No dose-dependent benefit observed: High-dose dexmedetomidine (1.0 μg/kg + 0.5 μg/kg/hour) did not further accelerate gastrointestinal recovery compared to low-dose (0.5 μg/kg + 0.2 μg/kg/hour). Low-dose regimen demonstrated superior safety: High-dose dexmedetomidine significantly increased intraoperative bradycardia risk (19.15% vs 8.19% in controls, P < 0.05). Reduced opioid/sedative requirements: Dexmedetomidine groups required less propofol and remifentanil than controls, potentially mitigating opioid-induced gastrointestinal dysfunction. Clinical recommendation: Low-dose dexmedetomidine is optimal for enhancing gastrointestinal recovery while minimizing cardiovascular risks. |
| Publish Date |
2025-08-18 10:04 |
| Citation |
<p>Chen Y, Tang WL, Li CT, Zhao Y, Li B, Liao LM, Lin TH, Zhang LC. Efficacy and safety of different doses of dexmedetomidine on gastrointestinal function recovery after laparoscopic colorectal surgery. <i>World J Gastroenterol</i> 2025; 31(31): 110582</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i31/110582.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i31.110582 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
