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Articles Published Processes
11/27/2025 7:53:54 AM | Browse: 4 | Download: 3
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Received |
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2025-06-12 04:02 |
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Peer-Review Started |
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2025-06-12 04:03 |
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First Decision by Editorial Office Director |
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2025-07-11 10:04 |
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Return for Revision |
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2025-07-13 03:11 |
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Revised |
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2025-07-14 12:07 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-09-28 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-28 08:18 |
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Articles in Press |
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2025-09-28 08:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-31 13:04 |
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Publish the Manuscript Online |
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2025-11-27 07:53 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zong-Yang Li, Cheng Xie and Hong-Qiao Cai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hong-Qiao Cai, MD, PhD, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. hongqiaocai@jlu.edu.cn |
| Key Words |
Hepatocellular carcinoma; Portal vein tumor thrombus; Liver transplantation; Downstaging therapy; Transarterial chemoembolization |
| Core Tip |
Hepatocellular carcinoma with portal vein tumor thrombus has long been considered a contraindication for liver transplantation due to poor prognosis. However, evolving downstaging strategies, including transarterial chemoembolization, transarterial radioembolization, proton beam therapy, and combination immunotherapies, have shown potential to convert select patients into transplant candidates. This review summarizes current clinical evidence and highlights future directions involving personalized medicine, novel biomaterials, and standardized criteria. |
| Publish Date |
2025-11-27 07:53 |
| Citation |
Li ZY, Xie C, Cai HQ. Pre-transplant downstaging strategies for hepatocellular carcinoma with portal vein tumor thrombus: Current therapies and future challenges. World J Hepatol 2025; 17(11): 110614 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i11/110614.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i11.110614 |
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