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Articles Published Processes
9/11/2025 9:42:01 AM | Browse: 259 | Download: 63
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Received |
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2025-06-11 02:32 |
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Peer-Review Started |
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2025-06-11 08:31 |
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To Make the First Decision |
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Return for Revision |
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2025-06-24 09:42 |
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Revised |
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2025-07-23 06:11 |
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Second Decision |
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2025-08-18 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-27 09:25 |
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Articles in Press |
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2025-08-27 09:25 |
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Publication Fee Transferred |
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2025-07-29 13:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-03 10:06 |
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Publish the Manuscript Online |
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2025-09-11 09:42 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Trends in baseline blood lipid levels in randomized placebo-controlled trials of overweight or obesity from 1990 to 2024
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Qi Wang, Quan-Zhou Xiao, Zhen-Ming Zhang and Yan Yang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yan Yang, Metabolic Syndrome Research Center, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410000, Hunan Province, China. 228201015@csu.edu.cn |
| Key Words |
Overweight; Obesity; Dyslipidemia; Lipid profile; Triglycerides; Cholesterol |
| Core Tip |
This global meta-analysis of 866 randomized trials (n = 3300) reveals significant improvements in lipid profiles among overweight/obese individuals over three decades, with triglycerides, total cholesterol and low-density lipoprotein-cholesterol declining while high-density lipoprotein-cholesterol increased. Notably, pharmacological interventions showed the most pronounced benefits. These findings highlight that despite rising obesity rates, concerted public health efforts and therapeutic advances have successfully mitigated dyslipidemia risks in this high-risk population, offering crucial insights for clinical practice and health policy. |
| Publish Date |
2025-09-11 09:42 |
| Citation |
<p>Wang YQ, Xiao QZ, Zhang ZM, Yang Y. Trends in baseline blood lipid levels in randomized placebo-controlled trials of overweight or obesity from 1990 to 2024. <i>World J Diabetes</i> 2025; 16(9): 110639</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i9/110639.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i9.110639 |
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