| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Respiratory System |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Impact of type 2 diabetes mellitus on interstitial lung disease risk in rheumatoid arthritis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jacob Sutton, Georges Khattar, Fares Saliba, Omar Mourad, Laurence Aoun, Jennifer Jdaidani, Hamzah Qandil, Chris Kaspar, Saif Abu-Baker, Shaza Almardini, Fadi Haddadin, Elie Bou Sanayeh and Anastasia Slobodnick |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jacob Sutton, MD, Internal Medicine, Staten Island University Hospital - Northwell Health, 475 Seaview Avenue, Staten Island, NY 10305, United States. jsutton2@northwell.edu |
| Key Words |
Rheumatoid arthritis; Diabetes mellitus; Interstitial lung disease; Pulmonary hypertension; Pulmonary fibrosis |
| Core Tip |
In this large inpatient study, we found that rheumatoid arthritis (RA) patients with type 2 diabetes have about twice the odds of developing interstitial lung disease compared to those without diabetes. This novel association remained significant after adjusting for numerous confounders. Diabetic RA patients also showed more pulmonary hypertension and pneumothorax. These results highlight the “diabetic lung” as a potential new consideration in RA care. Clinicians should be aware that co-morbid diabetes might heighten pulmonary risks in RA, although prospective studies are needed to confirm if controlling diabetes can improve lung outcomes. |
| Publish Date |
2025-11-21 03:54 |
| Citation |
<p>Sutton J, Khattar G, Saliba F, Mourad O, Aoun L, Jdaidani J, Qandil H, Kaspar C, Abu-Baker S, Almardini S, Haddadin F, Bou Sanayeh E, Slobodnick A. Impact of type 2 diabetes mellitus on interstitial lung disease risk in rheumatoid arthritis. <i>World J Clin Cases</i> 2025; 13(33): 110641</p> |
| URL |
https://www.wjgnet.com/2307-8960/full/v13/i33/110641.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v13.i33.110641 |
