| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Observational Study |
| Article Title |
Association between childhood maltreatment with subthreshold depressive symptoms and major depressive disorder in young and middle-aged adults
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing-Man Shi, Yu-Hua Liao, Yan-Zhi Li, Gia Han Le, Roger S McIntyre, Wei-Hong Zhang, Ines Keygnaert, Wan-Xin Wang, Lan Guo, Hui-Min Zhang, Cai-Hong Gao, Yan Chen, Xue Han and Ci-Yong Lu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82373660 and 81761128030 |
| Sanming Project of Medicine in Shenzhen Nanshan |
11 |
| the China Scholarship Council |
|
|
| Corresponding Author |
Ci-Yong Lu, Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, No. 74 Zhongshan Rd 2, Guangzhou 510080, Guangdong Province, China. luciyong@mail.sysu.edu.cn |
| Key Words |
Subthreshold depressive symptoms; Major depressive disorder; Childhood maltreatment; Adults |
| Core Tip |
This study investigates the association between childhood maltreatment and both subthreshold depressive symptoms (SDS) and major depressive disorder (MDD) in young and middle-aged adults. Our findings reveal that emotional abuse and neglect significantly contribute to depression risk across age groups, with emotional neglect showing a particularly strong association. This study extends previous literature by differentiating between SDS and MDD and underscores the need for trauma-informed care in depression management. Early identification of childhood maltreatment is crucial for preventing depression in at-risk individuals. |
| Publish Date |
2025-11-04 02:41 |
| Citation |
<p>Shi JM, Liao YH, Li YZ, Le GH, McIntyre RS, Zhang WH, Keygnaert I, Wang WX, Guo L, Zhang HM, Gao CH, Chen Y, Han X, Lu CY. Association between childhood maltreatment with subthreshold depressive symptoms and major depressive disorder in young and middle-aged adults. <i>World J Psychiatry</i> 2025; 15(11): 110648</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i11/110648.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i11.110648 |
