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Articles Published Processes
11/27/2025 7:53:52 AM | Browse: 74 | Download: 223
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Received |
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2025-06-13 06:28 |
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Peer-Review Started |
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2025-06-13 06:29 |
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First Decision by Editorial Office Director |
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2025-06-26 08:07 |
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Return for Revision |
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2025-06-26 08:07 |
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Revised |
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2025-07-08 03:02 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-09-02 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-02 06:46 |
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Articles in Press |
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2025-09-02 06:46 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-31 13:05 |
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Publish the Manuscript Online |
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2025-11-27 07:53 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Essential phospholipids and enzyme-based staging in nonalcoholic fatty liver disease: A call to action
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ali Madian |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ali Madian, Associate Professor, Consultant, MD, PhD, Department of Internal Medicine, Faculty of Medicine, Al-Azhar University-Assiut, Al Walideyah Al Bahreyah, Assiut 71524, Egypt. a.madian@azhar.edu.eg |
| Key Words |
Nonalcoholic fatty liver disease; Metabolic dysfunction-associated steatotic liver disease; Essential phospholipids; Liver enzymes; Noninvasive diagnostics; Ultrasonography |
| Core Tip |
The MANPOWER study demonstrated that Essentiale Forte N® reduces liver enzyme levels (alanine aminotransferase: 20-37 U/L, aspartate aminotransferase: 17-29 U/L, gamma-glutamyl transferase: 17-24 U/L, P < 0.001) and improves ultrasonography findings in patients with nonalcoholic fatty liver disease, with greater efficacy in severe cases. A liver enzyme-based algorithm offers 72.3% accuracy for noninvasive staging, prompting clinicians to adopt essential phospholipids and researchers to refine scalable diagnostics to address nonalcoholic fatty liver disease’s global burden. |
| Publish Date |
2025-11-27 07:53 |
| Citation |
Madian A. Essential phospholipids and enzyme-based staging in nonalcoholic fatty liver disease: A call to action. World J Hepatol 2025; 17(11): 110725 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i11/110725.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i11.110725 |
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