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Articles Published Processes
12/26/2025 10:27:29 AM | Browse: 1 | Download: 1
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Received |
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2025-06-18 11:00 |
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Peer-Review Started |
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2025-06-18 11:01 |
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First Decision by Editorial Office Director |
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2025-07-03 11:11 |
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Return for Revision |
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2025-07-05 03:41 |
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Revised |
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2025-07-17 20:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-11 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-11 10:08 |
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Articles in Press |
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2025-11-11 10:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-18 01:11 |
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Publish the Manuscript Online |
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2025-12-26 10:27 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Generic vs brand forms of direct acting antivirals for hepatitis C virus treatment in Egyptian children
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Engy Mogahed, Haytham Ghita, Afaf Enayet, Noha Yasin and Hanaa El-Karaksy |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hanaa El-Karaksy, Professor, The Pediatric Hepatology Unit, Department of Pediatrics, Cairo University, 44 Mohy-Eldien Abo Elezz Street, Cairo 12613, Egypt. hanaakaraksy@kasralainy.edu.eg |
| Key Words |
Children; Direct acting antivirals; Generic; Hepatitis C virus; Ledipasvir; Sofosbuvir |
| Core Tip |
Direct acting antivirals have revolutionized hepatitis C virus (HCV) treatment. The high price of the brand forms is a barrier for their use in resource limited countries. The use of the generic forms of direct acting antivirals in adult treatment programs has increased treatment coverage and changed the disease burden. Scanty data are available for their use in children. Our findings support the use of the generic form of sofosbuvir/ledipasvir in HCV infected children. The comparable efficacy and safety outcomes to the branded Harvoni® regimen, coupled with the cost advantages of generics, reinforce their value in national HCV control strategies. |
| Publish Date |
2025-12-26 10:27 |
| Citation |
Mogahed E, Ghita H, Enayet A, Yasin N, El-Karaksy H. Generic vs brand forms of direct acting antivirals for hepatitis C virus treatment in Egyptian children. World J Hepatol 2025; 17(12): 110726 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i12/110726.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i12.110726 |
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