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12/15/2025 9:46:10 AM | Browse: 58 | Download: 337
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Received |
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2025-06-16 01:17 |
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Peer-Review Started |
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2025-06-17 00:18 |
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First Decision by Editorial Office Director |
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2025-08-04 07:08 |
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2025-08-04 07:08 |
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Revised |
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2025-08-17 00:48 |
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Second Decision by Editor |
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2025-09-26 01:08 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-10 04:19 |
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Articles in Press |
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2025-11-10 04:19 |
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Edit the Manuscript by Language Editor |
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2025-11-15 02:25 |
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Typeset the Manuscript |
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2025-12-03 06:45 |
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Publish the Manuscript Online |
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2025-12-15 09:46 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Case Control Study |
| Article Title |
Association of ICAM-1 Gene Polymorphisms with Diabetic Retinopathy in T2DM Patients from Northern India: Case-control and meta-analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Navdeep Kaur, Shiwali Goyal, Indu R Singh and Vanita Vanita |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Department of Biotechnology, Government of India |
BT/IN/German/13/VK/2010 |
| Department of Science and Technology (DST), India |
SR/FT/LS-025/2008 |
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| Corresponding Author |
Vanita Vanita, PhD, Professor, Department of Human Genetics, Guru Nanak Dev University, GT Road, Amritsar 143005, Punjab, India. vanita.humangenetics@gmail.com |
| Key Words |
Diabetic retinopathy; DNA sequencing; Intercellular adhesion molecule-1; Type 2 diabetes mellitus; Northern India |
| Core Tip |
This study explores the association of ICAM-1 gene polymorphisms (rs5498 and rs1799969) with diabetic retinopathy (DR) in type 2 diabetes patients from northern India. A significant association was found between the rs5498 GG genotype and increased DR risk. A meta-analysis of nine studies revealed no consistent association overall or in Asians, but a significant association in Caucasians. This is the first report from northern India on ICAM-1 polymorphisms and DR, highlighting the importance of population-specific genetic risk assessment. |
| Publish Date |
2025-12-15 09:46 |
| Citation |
Kaur N, Goyal S, Singh IR, Vanita V. Association of ICAM-1 Gene Polymorphisms with Diabetic Retinopathy in T2DM Patients from Northern India: Case-control and meta-analysis. World J Diabetes 2025; 16(12): 110770 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i12/110770.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i12.110770 |
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