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Articles Published Processes
12/5/2025 11:28:03 AM | Browse: 6 | Download: 14
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Received |
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2025-06-17 01:51 |
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Peer-Review Started |
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2025-06-17 01:52 |
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First Decision by Editorial Office Director |
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2025-07-11 09:26 |
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Return for Revision |
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2025-07-11 09:26 |
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Revised |
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2025-07-14 09:46 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-23 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-23 09:03 |
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Articles in Press |
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2025-10-23 09:03 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-25 05:17 |
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Publish the Manuscript Online |
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2025-12-05 11:28 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Enteric nervous system as a therapeutic target in gastrointestinal disorders
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Himanshu Agrawal, Nitin Agarwal and Nikhil Gupta |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nikhil Gupta, Department of Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, BKS Marg, Delhi 110001, India. nikhil_ms26@yahoo.co.in |
| Key Words |
Enteric nervous system; Gastrointestinal motility disorders; Irritable bowel syndrome; Inflammatory bowel diseases; Neuroprotection |
| Core Tip |
The enteric nervous system (ENS) serves as a pivotal regulatory system within the gastrointestinal tract. Dysfunction in the ENS has been linked to a range of gastrointestinal disorders, including irritable bowel syndrome, gastroparesis, and inflammatory bowel diseases. Advances in therapeutic approaches targeting ENS pathways—ranging from neurotransmitter modulation to gene therapy—hold great promise for improving patient outcomes. By leveraging the gut-brain axis and focusing on restoring neural and glial cell function, these therapies represent a new frontier in gastrointestinal medicine. Targeting the ENS could offer a more effective, individualized approach to managing complex gastrointestinal diseases, providing significant improvements in symptom management and quality of life for affected patients. |
| Publish Date |
2025-12-05 11:28 |
| Citation |
Agrawal H, Agarwal N, Gupta N. Enteric nervous system as a therapeutic target in gastrointestinal disorders. World J Gastrointest Pharmacol Ther 2025; 16(4): 110843 |
| URL |
https://www.wjgnet.com/2150-5349/full/v16/i4/110843.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v16.i4.110843 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
