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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 110879
Country China
Received
2025-07-22 08:37
Peer-Review Started
2025-07-22 08:37
To Make the First Decision
Return for Revision
2025-08-08 07:16
Revised
2025-08-21 15:57
Second Decision
2025-09-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-15 06:32
Articles in Press
2025-09-15 06:32
Publication Fee Transferred
2025-08-25 09:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-17 02:28
Publish the Manuscript Online
2025-11-25 11:05
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Predictive value of systemic immune-inflammation index and serum lactoferrin for postoperative survival in older patients with colon cancer
Manuscript Source Unsolicited Manuscript
All Author List Sha-Sha Zhu, Tao Yang and Li-Li Cheng
ORCID
Author(s) ORCID Number
Sha-Sha Zhu http://orcid.org/0009-0008-3647-4802
Li-Li Cheng http://orcid.org/0009-0004-7061-7054
Funding Agency and Grant Number
Funding Agency Grant Number
Rugao Science and Technology Research and Development Program (Agriculture and Social Development) Project SRGS (24)061
Corresponding Author Li-Li Cheng, MD, Department of Laboratory, Rugao People's Hospital, No. 278 Ninghai Road, Rugao 226500, Jiangsu Province, China. 18051388531@163.com
Key Words Older patients with colon cancer; Systemic immune inflammation index; Serum lactoferrin level; Postoperative survival; Disease-free survival; Prognostic biomarkers
Core Tip This study prospectively evaluated the predictive value of systemic immune-inflammation index (SII) combined with serum lactoferrin (LF) levels for survival outcomes in older patients with colon cancer undergoing radical surgery. Dynamic monitoring demonstrated that preoperative SII and LF levels were independent predictors of overall survival and disease-free survival. The findings suggest that SII and LF serve as simple and effective prognostic biomarkers, providing valuable guidance for individualized treatment strategies and postoperative recurrence risk assessment in elderly colon cancer patients.
Publish Date 2025-11-25 11:05
Citation <p>Zhu SS, Yang T, Cheng LL. Predictive value of systemic immune-inflammation index and serum lactoferrin for postoperative survival in older patients with colon cancer. <i>World J Gastrointest Surg</i> 2025; 17(11): 110879</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i11/110879.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i11.110879
Full Article (PDF) WJGS-17-110879-with-cover.pdf
CONSORT 2010 Statement 110879-CONSORT-2010-statement.pdf
Manuscript File 110879_Auto_Edited_083853.docx
Answering Reviewers 110879-answering-reviewers.pdf
Audio Core Tip 110879-audio.mp3
Biostatistics Review Certificate 110879-biostatistics-statement.pdf
Clinical Trial Registration Statement 110879-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 110879-conflict-of-interest-statement.pdf
Copyright License Agreement 110879-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 110879-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 110879-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 110879-non-native-speakers.pdf
Peer-review Report 110879-peer-reviews.pdf
Scientific Misconduct Check 110879-scientific-misconduct-check.png
Scientific Editor Work List 110879-scientific-editor-work-list.pdf
CrossCheck Report 110879-crosscheck-report.pdf