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Articles Published Processes
12/23/2025 8:03:22 AM | Browse: 9 | Download: 16
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Received |
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2025-06-18 09:49 |
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Peer-Review Started |
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2025-06-18 09:49 |
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First Decision by Editorial Office Director |
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2025-06-24 10:57 |
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Return for Revision |
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2025-06-24 10:57 |
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Revised |
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2025-07-08 07:37 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-13 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-13 03:43 |
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Articles in Press |
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2025-10-13 03:43 |
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Edit the Manuscript by Language Editor |
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2025-10-17 01:28 |
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Typeset the Manuscript |
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2025-12-16 00:18 |
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Publish the Manuscript Online |
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2025-12-23 08:03 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Review |
| Article Title |
Role of antiphospholipid antibodies in kidney disease: Risk factors, immunopathogenesis, and diagnosis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Khawar Abbas, Rubina Naqvi, Wajiha Musharraf, Muhammed Mubarak and Jawahar Lal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Khawar Abbas, Professor, Department of Immunology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drkhawar_imuno@yahoo.com |
| Key Words |
Kidney infarction; Allograft; Thrombosis; Antiphospholipid antibodies; Antiphospholipid nephropathy; Antiphospholipid syndrome |
| Core Tip |
Antiphospholipid syndrome (APS) is an autoimmune disorder defined by the presence of antiphospholipid antibodies (aPLs) such as anticardiolipin, anti-β2 glycoprotein 1, and lupus anticoagulant. Renal involvement is a significant yet underrecognized complication of both primary and secondary APS. Manifestations include renal artery and vein thrombosis, APS nephropathy (APSN), and renal allograft thrombosis. APSN, a hallmark of renal APS, results from vaso-occlusive injury to the intrarenal microvasculature. Accurate diagnosis and risk assessment remain challenging due to evolving criteria and heterogeneous presentation. This review consolidates current evidence on APS and APSN, emphasizing risk factors, underlying mechanisms, and diagnostic approaches. |
| Publish Date |
2025-12-23 08:03 |
| Citation |
Abbas K, Naqvi R, Musharraf W, Mubarak M, Lal J. Role of antiphospholipid antibodies in kidney disease: Risk factors, immunopathogenesis, and diagnosis. World J Nephrol 2025; 14(4): 110882 |
| URL |
https://www.wjgnet.com/2220-6124/full/v14/i4/110882.htm |
| DOI |
https://dx.doi.org/10.5527/wjn.v14.i4.110882 |
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