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Articles Published Processes
12/19/2025 8:32:44 AM | Browse: 4 | Download: 6
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Received |
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2025-06-19 06:56 |
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Peer-Review Started |
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2025-06-19 06:56 |
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First Decision by Editorial Office Director |
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2025-07-16 08:35 |
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Return for Revision |
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2025-07-16 08:35 |
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Revised |
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2025-07-25 10:09 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-17 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-17 08:59 |
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Articles in Press |
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2025-11-17 08:59 |
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Edit the Manuscript by Language Editor |
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2025-11-20 15:43 |
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Typeset the Manuscript |
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2025-12-08 09:02 |
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Publish the Manuscript Online |
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2025-12-19 08:32 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pathology |
| Manuscript Type |
Basic Study |
| Article Title |
Evaluating palmitoyl-protein thioesterase 1 in oral squamous cell carcinoma: A novel indicator of tumor behavior and therapeutic response
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kurundhalingam Chinniah Pradheep Kumar, Sanjukta Sahoo, Amit Kumar Adhya, Manisha R Gaikwad, Arthi Ganapathy and Praveen Kumar Ravi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Praveen Kumar Ravi, Assistant Professor, MD, Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Sijua, Patrapada, Bhubaneswar 751019, Odisha, India. praveenkumar1059@gmail.com |
| Key Words |
Oral squamous cell carcinoma; Protein palmitoyl thioesterase-1; H-score; Prognostic biomarker; Tumor grade; TNM staging; Immunohistochemistry |
| Core Tip |
This study explores the expression of palmitoyl-protein thioesterase 1 (PPT1) in oral squamous cell carcinoma (OSCC) using immunohistochemistry and H-score quantification. A strong positive correlation was observed between PPT1 expression and tumor grade, while a negative correlation was seen with age. These findings suggest that PPT1 may serve as a novel prognostic and therapeutic biomarker, especially in younger patients and advanced OSCC cases. The study highlights the potential of integrating molecular biomarkers like PPT1 with conventional histopathological evaluation to guide personalised treatment strategies in OSCC. |
| Publish Date |
2025-12-19 08:32 |
| Citation |
Kumar KCP, Sahoo S, Adhya AK, Gaikwad MR, Ganapathy A, Ravi PK. Evaluating palmitoyl-protein thioesterase 1 in oral squamous cell carcinoma: A novel indicator of tumor behavior and therapeutic response. World J Exp Med 2025; 15(4): 110917 |
| URL |
https://www.wjgnet.com/2220-315x/full/v15/i4/110917.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v15.i4.110917 |
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