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Articles Published Processes
10/27/2025 8:08:13 AM | Browse: 107 | Download: 155
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Received |
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2025-06-19 10:47 |
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Peer-Review Started |
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2025-06-19 10:49 |
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First Decision by Editorial Office Director |
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2025-07-17 10:28 |
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Return for Revision |
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2025-07-17 10:28 |
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Revised |
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2025-07-29 08:08 |
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Publication Fee Transferred |
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2025-08-01 04:11 |
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Second Decision by Editor |
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2025-09-16 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-16 04:02 |
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Articles in Press |
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2025-09-16 04:02 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-21 01:48 |
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Publish the Manuscript Online |
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2025-10-27 08:08 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Serum gamma-glutamyl transferase level is associated with the risk of pancreatic cystic neoplasms: A nationwide retrospective cohort study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Min Woo Lee, Jin Myung Park, In Rae Cho, Kwang Hyun Chung, Bong Seong Kim, Jin Ho Choi, Woo Hyun Paik, Ji Kon Ryu, Kyungdo Han and Sang Hyub Lee |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sang Hyub Lee, Professor, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea. gidoctor@snu.ac.kr |
| Key Words |
Pancreatic cystic neoplasm; Gamma-glutamyl transferase; Biomarker; Cohort study; Epidemiology |
| Core Tip |
Gamma-glutamyl transferase (GGT), a marker of oxidative stress and hepatic dysfunction, has been reported to be associated with metabolic diseases and malignancies including pancreatic cancer. However, its role in pancreatic cystic neoplasm (PCN) has not been investigated. In this nationwide retrospective cohort study of over 2.6 million people, higher serum GGT levels were independently associated with an increased risk of PCN. This association remained robust in subgroup and sensitivity analyses when adjusting for lag period and GGT categorization. This is the first large-scale study suggesting GGT as a potential biomarker for identifying individuals at high risk of PCN. |
| Publish Date |
2025-10-27 08:08 |
| Citation |
Lee MW, Park JM, Cho IR, Chung KH, Kim BS, Choi JH, Paik WH, Ryu JK, Han K, Lee SH. Serum gamma-glutamyl transferase level is associated with the risk of pancreatic cystic neoplasms: A nationwide retrospective cohort study. World J Gastroenterol 2025; 31(40): 110932 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i40/110932.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i40.110932 |
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