| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Epidemiology of dyspepsia and esophagogastroduodenoscopic findings in the era of Helicobacter pylori eradication
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Suguo Suzuki, Takeshi Kanno, Tomoyuki Koike, Takashi Chiba, Kiyotaka Asanuma, Katsuaki Kato, Yutaka Hatayama, Yohei Ogata, Masahiro Saito, Waku Hatta, Kaname Uno, Akira Imatani and Atsushi Masamune |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Takeshi Kanno, Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 9808575, Miyagi, Japan. kanno.takeshi@med.tohoku.ac.jp |
| Key Words |
Dyspepsia; Helicobacter pylori; Endoscopy; Peptic ulcers; Mass screening |
| Core Tip |
We analyzed over 23000 adults undergoing endoscopic gastric cancer screening in Japan to assess dyspepsia prevalence across Helicobacter pylori infection statuses. Dyspepsia was most prevalent (28.7%) in the post-eradication and non-infected groups, compared to 25.8% in the currently infected group. Younger age, female sex, peptic ulcers, erosive esophagitis, and post-eradication status were independently associated with dyspepsia. Despite extensive endoscopic evaluation, over 90% of cases had no organic findings. These results highlight the evolving nature of dyspepsia and its persistence in the post-Helicobacter pylori era. |
| Publish Date |
2025-09-25 03:33 |
| Citation |
<p>Suzuki S, Kanno T, Koike T, Chiba T, Asanuma K, Kato K, Hatayama Y, Ogata Y, Saito M, Hatta W, Uno K, Imatani A, Masamune A. Epidemiology of dyspepsia and esophagogastroduodenoscopic findings in the era of Helicobacter pylori eradication. <i>World J Gastroenterol</i> 2025; 31(37): 110942</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i37/110942.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i37.110942 |
