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Articles Published Processes
12/26/2025 10:27:35 AM | Browse: 3 | Download: 1
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Received |
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2025-06-20 02:06 |
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Peer-Review Started |
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2025-06-20 02:06 |
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First Decision by Editorial Office Director |
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2025-07-08 09:25 |
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Return for Revision |
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2025-07-08 09:25 |
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Revised |
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2025-08-13 14:17 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-03 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-03 05:42 |
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Articles in Press |
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2025-12-03 05:42 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-18 01:02 |
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Publish the Manuscript Online |
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2025-12-26 10:27 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Health Care Sciences & Services |
| Manuscript Type |
Minireviews |
| Article Title |
Refractory autoimmune hepatitis in children: Considerations for assessment and management
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Joseph Valamparampil, Rachel M Brown and Patrick Mckiernan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Joseph Valamparampil, MD, Liver unit (including small bowel transplantation), Birmingham Women’s and Children's NHS Foundation Trust, Steel house Lane, Birmingham B4 6NH, United Kingdom. joseph.valam@nhs.net |
| Key Words |
Autoimmune hepatitis; Refractory; Remission; Treatment; Non-compliance |
| Core Tip |
Treatment of autoimmune hepatitis seeks to induce and maintain remission, prevent progression, and potentially reverse fibrosis. In the 10%-20% of children unresponsive to steroids and azathioprine, adherence to medication and diagnosis should be reassessed and mimicking diseases excluded. Mycophenolate mofetil is the preferred second-line agent. Further therapy should be individualized, with adjustments made only after 6-12 months. |
| Publish Date |
2025-12-26 10:27 |
| Citation |
Valamparampil J, Brown RM, Mckiernan P. Refractory autoimmune hepatitis in children: Considerations for assessment and management. World J Hepatol 2025; 17(12): 110966 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i12/110966.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i12.110966 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
