| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Stereotactic body radiation therapy in patients with unresectable hepatocellular carcinoma and portal vein tumor thrombosis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Divya Khosla, Venkata Krishna Vamsi Gade, Rakesh Kapoor, Gaganpreet Singh, Ranjit Singh, Sunil Taneja, Madhumita Premkumar, Naveen Kalra, Arka De, Harish Bhujade, Nipun Verma, Ajay Duseja and Rajesh Gupta |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Divya Khosla, Additional Professor, MD, Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Room No 54, Radiotherapy and Oncology Office, Ground Floor, Nehru Hospital Extension, Chandigarh 160012, India. dr_divya_khosla@yahoo.com |
| Key Words |
Hepatocellular carcinoma; Portal venous tumor thrombosis; Stereotactic body radiation therapy; Kaplan-Meier curves; Barcelona clinic liver cancer |
| Core Tip |
Portal vein tumor thrombosis is a common and challenging presentation in hepatocellular carcinoma, significantly limiting treatment options. This retrospective study highlights the safety and efficacy of stereotactic body radiation therapy as a locoregional treatment in patients with unresectable hepatocellular carcinoma and portal vein tumor thrombosis. With an encouraging response rate of 83.3% and a median overall survival of 13 months, stereotactic body radiation therapy demonstrates promising early outcomes and minimal toxicity, supporting its role as a viable therapeutic option in this difficult-to-treat population. |
| Publish Date |
2025-12-26 10:27 |
| Citation |
Khosla D, Gade VKV, Kapoor R, Singh G, Singh R, Taneja S, Premkumar M, Kalra N, De A, Bhujade H, Verma N, Duseja A, Gupta R. Stereotactic body radiation therapy in patients with unresectable hepatocellular carcinoma and portal vein tumor thrombosis. World J Hepatol 2025; 17(12): 110993 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i12/110993.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i12.110993 |
