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1/30/2026 6:45:46 AM | Browse: 3 | Download: 14
Publication Name World Journal of Psychiatry
Manuscript ID 111012
Country China
Received
2025-08-01 08:00
Peer-Review Started
2025-08-01 08:00
First Decision by Editorial Office Director
2025-08-20 07:01
Return for Revision
2025-08-20 07:01
Revised
2025-09-12 16:00
Publication Fee Transferred
2025-09-19 08:28
Second Decision by Editor
2025-11-11 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-11 10:18
Articles in Press
2025-11-11 10:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-18 03:55
Publish the Manuscript Online
2026-01-30 06:45
ISSN 2220-3206 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology
Manuscript Type Observational Study
Article Title Characteristics and functions of the gut microbiome in monozygotic twins with autism spectrum disorders of varying severity
Manuscript Source Unsolicited Manuscript
All Author List Yi-Yang Huang, Chun-Yan Li, Yun Li, Hui Fang and Xiao-Yan Ke
ORCID
Author(s) ORCID Number
Xiao-Yan Ke http://orcid.org/0009-0007-7526-3875
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 8177050957
Corresponding Author Xiao-Yan Ke, PhD, Child Mental Health Research Center, the Affiliated Brain Hospital of Nanjing Medical University, No.264 Guangzhou Road, Gulou Distric, Nanjing 210000, Jiangsu Province, China. kexynj@126.com
Key Words Autism spectrum disorder; Gut microbiome; Nonshared environmental factors; Monozygotic twins; g-Porphyromonas
Core Tip Autism spectrum disorder (ASD) is a highly heritable and heterogeneous neurodevelopmental disorder. Diagnostic and treatment options remain limited. Researchers are increasingly investigating the relationship between gut dysbiosis and ASD. This study examined gut microbiota composition and functions in monozygotic twins with varying ASD severity levels. Enrichment of Porphyromonas and reduced expression of genes involved in carbohydrate metabolism and stress responses were observed, suggesting a correlation between gut microbial dysbiosis and ASD severity.
Publish Date 2026-01-30 06:45
Citation

Huang YY, Li CY, Li Y, Fang H, Ke XY. Characteristics and functions of the gut microbiome in monozygotic twins with autism spectrum disorders of varying severity. World J Psychiatry 2026; 16(2): 111012

URL https://www.wjgnet.com/2220-3206/full/v16/i2/111012.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i2.111012
Full Article (PDF) WJP-16-111012-with-cover.pdf
STROBE Statement 111012-STROBE-statement.pdf
Manuscript File 111012_Auto_Edited_022334.docx
Answering Reviewers 111012-answering-reviewers.pdf
Audio Core Tip 111012-audio.mp3
Biostatistics Review Certificate 111012-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111012-conflict-of-interest-statement.pdf
Copyright License Agreement 111012-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111012-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111012-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111012-non-native-speakers.pdf
Peer-review Report 111012-peer-reviews.pdf
Scientific Misconduct Check 111012-scientific-misconduct-check.png
Scientific Editor Work List 111012-scientific-editor-work-list.pdf
CrossCheck Report 111012-crosscheck-report.pdf