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Articles Published Processes
3/6/2026 8:56:30 AM | Browse: 5 | Download: 12
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Received |
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2025-06-23 10:33 |
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Peer-Review Started |
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2025-06-23 10:35 |
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First Decision by Editorial Office Director |
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2025-07-02 08:50 |
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Return for Revision |
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2025-07-02 08:50 |
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Revised |
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2025-07-10 15:52 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-06 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-07 03:48 |
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Articles in Press |
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2025-11-07 03:48 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-03 00:36 |
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Publish the Manuscript Online |
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2026-03-06 08:56 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Minireviews |
| Article Title |
Therapeutic interventions and pulmonary function in pediatric patients with post-infectious bronchiolitis obliterans
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Serena Chiellino |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Serena Chiellino, MD, Paediatric and Neonatologic Unit, Santo Stefano Hospital, Via Suor Niccolina Infermiera 20/22, Prato 59100, Tuscany, Italy. serenachiellino90@gmail.com |
| Key Words |
Post-infectious bronchiolitis obliterans; Pediatric pulmonary function; Children; Therapeutic interventions; Spirometric monitoring |
| Core Tip |
Post-infectious bronchiolitis obliterans leads to permanent small-airway obstruction and significant spirometric deficits in children, notably reduced forced expiratory volume in one second and forced expiratory flow at 25%-75% with poor bronchodilator response, while diffusing capacity of the lung for carbon monoxide often remains normal. This narrative review links these pulmonary function parameters with therapeutic interventions, showing that early use of inhaled or systemic corticosteroids and macrolides can stabilize or modestly improve lung function. Emerging combination regimens, such as fluticasone-azithromycin-montelukast, show promise but need further validation. Integrating regular spirometric monitoring with tailored anti-inflammatory strategies may optimize clinical outcomes and underlines the need for prospective studies. |
| Publish Date |
2026-03-06 08:56 |
| Citation |
Chiellino S. Therapeutic interventions and pulmonary function in pediatric patients with post-infectious bronchiolitis obliterans. World J Clin Pediatr 2026; 15(1): 111021 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i1/111021.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i1.111021 |
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