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Articles Published Processes
4/23/2026 11:05:50 AM | Browse: 1 | Download: 12
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Received |
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2025-06-23 10:40 |
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Peer-Review Started |
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2025-06-23 10:41 |
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First Decision by Editorial Office Director |
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2025-08-04 07:46 |
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Return for Revision |
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2025-08-04 07:46 |
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Revised |
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2025-08-09 03:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-11 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-11 08:50 |
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Articles in Press |
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2025-11-11 08:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-30 05:25 |
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Publish the Manuscript Online |
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2026-04-23 11:05 |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Clinical insights into levothyroxine overdose: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fateen Ata, Haseeb Ahmad Khan, Aamna Kashif, Adeel Ahmad Khan, Rabia Fawad, Hafiz Waqas Younas, Bilal Ahmed and Huzaifa Javed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Fateen Ata, Internal Medicine, Cleveland Clinic Foundation, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar
PO BOX 3050, Cleveland, OH 44118, United States. docfateenata@gmail.com |
| Key Words |
Levothyroxine; Overdose; Toxicity; Thyroid; Suicide; Thyroxine |
| Core Tip |
This systematic review presents the most comprehensive data synthesis on levothyroxine (LTX) overdose (OD) across all age groups. It highlights key clinical patterns that distinguish unintentional pediatric OD from intentional adult OD, with the latter exhibiting more prominent symptom severity. Despite wide dose variability, mortality was rare. Most cases were managed conservatively. Extracorporeal modalities were employed in cases that were severe and refractory. This systematic review highlights the need for treatment protocols and prevention strategies for LTX toxicity, providing valuable insights for clinicians managing thyroid hormone toxicity. |
| Publish Date |
2026-04-23 11:05 |
| Citation |
Ata F, Khan HA, Kashif A, Khan AA, Fawad R, Younas HW, Ahmed B, Javed H. Clinical insights into levothyroxine overdose: A systematic review. World J Methodol 2026; 16(2): 111025 |
| URL |
https://www.wjgnet.com/2222-0682/full/v16/i2/111025.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v16.i2.111025 |
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