Publication Name	World Journal of Gastroenterology
Manuscript ID	11103
Country	Thailand

Received	2014-05-05 08:45
Peer-Review Started	2014-05-05 19:16
To Make the First Decision	2014-07-21 13:40
Return for Revision	2014-07-28 13:53
Revised	2014-08-06 16:31
Second Decision	2014-09-05 16:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-05 17:06
Articles in Press	2014-09-05 17:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-09-15 22:19
Typeset the Manuscript	2014-12-18 10:09
Publish the Manuscript Online	2015-01-06 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Aloe vera attenuated gastric injury on indomethacin-induced gastropathy in rats
Manuscript Source	Unsolicited Manuscript
All Author List	Duangporn Werawatganon, Narisorn Rakananurak, Sasipim Sallapant, Piyapan Prueksapanich, Kanjana Somanawat, Naruemon Klaikeaw and Rungsun Rerknimitr
Funding Agency and Grant Number	Funding Agency Grant Number 90th Anniversary Fund of Chulalongkorn University (Ratchada phiseksomphot Endowment Fund) The Grant of Ratchadaphiseksomphot, Faculty of Medicine, Chulalongkorn University
Corresponding Author	Duangporn Werawatganon, MD, Associate Professor, Department of Physiology, Faculty of Medicine, Chulalongkorn University, 254 Phyathai Road, Patumwan, Bangkok 10330, Thailand. dr.duangporn@gmail.com
Key Words	Aloe vera; Indomethacin; Gastric injury; Gastropathy; Tumor necrosis factor-a; cytokine-induced neutrophil chemoattractant-1; malondialdehyde; interleukin-18
Core Tip	Nonsteroidal anti-inflammatory drugs (NSAIDs)-induced gastric damage is the major side effect of this kind of medication. Although the underlying pathogenesis of NSAIDs-induced gastric damage is unclear, neutrophils are believed to play an important role in the development of gastric inflammation and injury following NSAIDs administration. Aloe vera (Aloe barbadensis Mill) possesses several biological activities, including an anti-inflammatory and ulcer healing effects. The authors postulated that Aloe vera, acting through inflammatory inhibition, could reduce the inflammatory cytokine, neutrophil chemoattractant, and oxidative stress thus resulting in attenuation of gastric injury in indomethacin-induced gastropathy in rats.
Publish Date	2015-01-06 09:08
Citation	Werawatganon D, Rakananurak N, Sallapant S, Prueksapanich P, Somanawat K, Klaikeaw N, Rerknimitr R. Aloe vera attenuated gastric injury on indomethacin-induced gastropathy in rats. World J Gastroenterol 2014; 20(48): 18330-18337
URL	http://www.wjgnet.com/1007-9327/full/v20/i48/18330.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i48.18330

Full Article (PDF)	WJG-20-18330.pdf
Full Article (Word)	WJG-20-18330.doc
Manuscript File	11103-Review.doc
Answering Reviewers	11103-Answering reviewers.pdf
Copyright License Agreement	11103-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11103-Language certificate.pdf
Peer-review Report	11103-Peer reviewers.pdf
Scientific Misconduct Check	11103-CrossCheck.jpg
Scientific Editor Work List	11103-Scientific editor work list.pdf