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3/6/2026 8:56:27 AM | Browse: 3 | Download: 14
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 111030
Country India
Received
2025-06-23 06:24
Peer-Review Started
2025-06-23 06:25
First Decision by Editorial Office Director
2025-07-16 08:32
Return for Revision
2025-07-16 08:32
Revised
2025-07-24 14:57
Publication Fee Transferred
Second Decision by Editor
2025-10-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-28 02:44
Articles in Press
2025-10-28 02:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-01 17:19
Publish the Manuscript Online
2026-03-06 08:56
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Systematic Reviews
Article Title Interplay of childhood metabolic dysfunction-associated steatotic liver disease and obesity in the development of youth-onset type 2 diabetes
Manuscript Source Invited Manuscript
All Author List Razieh Parizad, Juniali Hatwal, Ajit Singh Brar, Leila Alizadeh, Manjeet Kumar Goyal, Akash Batta and Bishav Mohan
ORCID
Author(s) ORCID Number
Razieh Parizad http://orcid.org/0000-0002-4492-637X
Juniali Hatwal http://orcid.org/0000-0001-5433-0433
Ajit Singh Brar http://orcid.org/0000-0002-5317-3357
Leila Alizadeh http://orcid.org/0000-0001-9764-7713
Manjeet Kumar Goyal http://orcid.org/0000-0002-5511-2099
Akash Batta http://orcid.org/0000-0002-7606-5826
Bishav Mohan http://orcid.org/0000-0002-4337-3603
Funding Agency and Grant Number
Corresponding Author Akash Batta, DM, MD, Department of Cardiology, Dayanand Medical College and Hospital, Tagore Nagar, Civil Lines, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com
Key Words Pediatric; Metabolic dysfunction-associated steatotic liver disease; Childhood obesity; Type 2 diabetes mellitus; Metabolic syndrome; Non-alcoholic fatty liver disease; Insulin resistance
Core Tip The global increase in childhood and adolescent obesity has significantly contributed to the rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) – a metabolic complication with significant extrahepatic manifestations in the youth. MASLD represents a critical metabolic threat in pediatric populations, strongly influenced by obesity and is closely associated with increased risk of youth-onset type 2 diabetes (T2D). This comprehensive literature search synthesizes the current evidence on the epidemiological trends, pathophysiological mechanisms, psychological impact, diagnostic challenges, management and prevention strategies related to MASLD in the pediatric population, with particular emphasis on its interplay with obesity and youth-onset T2D.
Publish Date 2026-03-06 08:56
Citation

Parizad R, Hatwal J, Brar AS, Alizadeh L, Goyal MK, Batta A, Mohan B. Interplay of childhood metabolic dysfunction-associated steatotic liver disease and obesity in the development of youth-onset type 2 diabetes. World J Clin Pediatr 2026; 15(1): 111030

URL https://www.wjgnet.com/2219-2808/full/v15/i1/111030.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i1.111030
Full Article (PDF) WJCP-15-111030-with-cover.pdf
PRISMA 2009 Checklist 111030-PRISMA-2009-Checklist.pdf
Manuscript File 111030_Auto_Edited_033842.docx
Answering Reviewers 111030-answering-reviewers.pdf
Audio Core Tip 111030-audio.m4a
Biostatistics Review Certificate 111030-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111030-conflict-of-interest-statement.pdf
Copyright License Agreement 111030-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111030-non-native-speakers.pdf
Supplementary Material 111030-supplementary-material.pdf
Peer-review Report 111030-peer-reviews.pdf
Scientific Misconduct Check 111030-scientific-misconduct-check.png
Scientific Editor Work List 111030-scientific-editor-work-list.pdf
CrossCheck Report 111030-crosscheck-report.pdf