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12/25/2025 8:27:20 AM | Browse: 2 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 111041
Country China
Received
2025-07-29 08:46
Peer-Review Started
2025-07-29 08:46
First Decision by Editorial Office Director
2025-08-11 03:34
Return for Revision
2025-08-11 03:34
Revised
2025-09-02 09:36
Publication Fee Transferred
2025-09-03 08:44
Second Decision by Editor
2025-10-16 02:53
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-17 02:00
Articles in Press
2025-10-17 02:00
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-15 02:50
Publish the Manuscript Online
2025-12-25 08:27
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Associations of clinical indexes and prognosis with gut-vascular barrier damage in patients with intestinal obstruction
Manuscript Source Unsolicited Manuscript
All Author List Hu-Fei Zhang, Yi Guo, Xiao-Jun Chen, Yi-Nan Zhang, Hui Peng, Zi-Meng Liu and Xu-Yu Zhang
ORCID
Author(s) ORCID Number
Hu-Fei Zhang http://orcid.org/0009-0002-9549-3030
Yi Guo http://orcid.org/0009-0008-5762-4777
Xiao-Jun Chen http://orcid.org/0009-0001-5975-331X
Yi-Nan Zhang http://orcid.org/0009-0000-0317-1786
Hui Peng http://orcid.org/0009-0003-9404-6017
Zi-Meng Liu http://orcid.org/0000-0001-6499-564X
Xu-Yu Zhang http://orcid.org/0000-0002-0637-3049
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82072204
National Natural Science Foundation of China 81701874
Natural Science Foundation of Guangdong Province, China 2021A1515010990
Natural Science Foundation of Guangdong Province, China 2025A1515012493
Corresponding Author Xu-Yu Zhang, MD, PhD, Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, No.58, Zhongshan 2th Road, Guangzhou 510080, Guangdong Province, China. zhangxuy@mail.sysu.edu.cn
Key Words Intestinal obstruction; Gut-vascular barrier; PV1; Infection; Organ injury; Clinical prognosis
Core Tip This study reveals that intestinal obstruction (IO) leads to gut-vascular barrier (GVB) damage, with PV1 expression positively correlating with infection, liver/kidney injury, and adverse outcomes. GVB impairment may contribute to IO pathogenesis, highlighting PV1 as a potential prognostic biomarker.
Publish Date 2025-12-25 08:27
Citation

Zhang HF, Guo Y, Chen XJ, Zhang YN, Peng H, Liu ZM, Zhang XY. Associations of clinical indexes and prognosis with gut-vascular barrier damage in patients with intestinal obstruction. World J Gastrointest Surg 2025; 17(12): 111041

URL https://www.wjgnet.com/1948-9366/full/v17/i12/111041.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i12.111041
Full Article (PDF) WJGS-17-111041-with-cover.pdf
STROBE Statement 111041-STROBE-statement.pdf
Manuscript File 111041_Auto_Edited_021644.docx
Answering Reviewers 111041-answering-reviewers.pdf
Audio Core Tip 111041-audio.m4a
Biostatistics Review Certificate 111041-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111041-conflict-of-interest-statement.pdf
Copyright License Agreement 111041-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111041-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111041-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111041-non-native-speakers.pdf
Supplementary Material 111041-supplementary-material.pdf
Peer-review Report 111041-peer-reviews.pdf
Scientific Misconduct Check 111041-scientific-misconduct-check.png
Scientific Editor Work List 111041-scientific-editor-work-list.pdf
CrossCheck Report 111041-crosscheck-report.pdf