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Articles Published Processes
11/28/2025 2:00:52 PM | Browse: 24 | Download: 59
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Received |
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2025-06-23 13:41 |
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Peer-Review Started |
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2025-06-23 13:41 |
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First Decision by Editorial Office Director |
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2025-06-27 05:42 |
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Return for Revision |
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2025-06-27 05:42 |
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Revised |
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2025-07-08 08:36 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-09 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-10 06:54 |
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Articles in Press |
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2025-10-10 06:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-17 01:52 |
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Publish the Manuscript Online |
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2025-11-28 14:00 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Ivabradine in acute care: Revisiting the funny current in critical care context
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Arun Mukesh, Ankur Sharma and Nikhil Kothari |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ankur Sharma, Additional Professor, Consultant, MD, Department of Trauma and Emergency (Anaesthesiology and Critical Care), All India Institute of Medical Sciences, Corresponding Author: Ankur Sharma, E-mail: <email>ankuranaesthesia@gmail.com</email>, Jodhpur 342008, Rājasthān, India. ankuranaesthesia@gmail.com |
| Key Words |
Ivabradine; Heart rate control; Tachycardia; Heart failure; Beta blocker; Acute care |
| Core Tip |
Ivabradine reduces heart rate by specifically inhibiting the funny current in the sinoatrial node, without impacting myocardial contractility or blood pressure. This distinctive characteristic renders it an appealing choice for critically sick patients for whom beta-blockers are contraindicated or poorly tolerated. Recent studies corroborate its significance in acute scenarios, including acute decompensated heart failure, acute coronary syndrome, and sepsis-induced tachycardia, where a higher heart rate exacerbates outcomes. This review looks at the mechanism of action, clinical uses, comparative effectiveness, and safety profile. |
| Publish Date |
2025-11-28 14:00 |
| Citation |
Mukesh A, Sharma A, Kothari N. Ivabradine in acute care: Revisiting the funny current in critical care context. World J Crit Care Med 2025; 14(4): 111054 |
| URL |
https://www.wjgnet.com/2220-3141/full/v14/i4/111054.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v14.i4.111054 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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