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9/10/2025 7:53:43 AM | Browse: 199 | Download: 20
Publication Name World Journal of Orthopedics
Manuscript ID 111068
Country United States
Received
2025-06-23 06:20
Peer-Review Started
2025-06-23 06:20
To Make the First Decision
Return for Revision
2025-07-19 01:53
Revised
2025-08-03 07:07
Second Decision
2025-08-27 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-27 08:47
Articles in Press
2025-08-27 08:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-04 03:36
Publish the Manuscript Online
2025-09-10 07:53
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Meta-Analysis
Article Title Outcomes of autologous bone grafts vs bone substitutes in tibial plateau fractures: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Ali Saad Alshahrani, Yazan Jumah Alalwani, Nihal Mushabb Alqahtani, Abdullah Shafi D Alanazi, Ahmed Khaled Almarri, Shatha Saud Alqurashi, Deemah Khalid Ghazi, Abdullah Musaaed Alsalamah, Rahaf Hamdan Alruwaili, Ahmed Y Azzam and Fawaz Alanii
ORCID
Author(s) ORCID Number
Ahmed Y Azzam http://orcid.org/0000-0002-4256-0159
Funding Agency and Grant Number
Corresponding Author Ahmed Y Azzam, Director of Clinical Research and Clinical Artificial Intelligence, ASIDE Healthcare, 16192 Coastal Highway, Lewes, Delaware 19958, United States. ahmedyazzam@gmail.com
Key Words Tibial plateau fractures; Tibia; Bone grafts; Bone substitutes; Synthetic bone material
Core Tip This meta-analysis of seven randomized controlled trials involving 424 patients demonstrates that bone substitutes provide equivalent structural outcomes to autologous bone grafts in tibial plateau fractures while offering significant procedural advantages. The study introduces a novel combined outcome scoring system integrating structural, procedural, and complication domains, revealing bone substitutes reduce blood loss by 70-90 mL and operative time, particularly in Asian populations. Geographic variations showed Western studies had 45% higher secondary collapse risk with autografts. These findings support bone substitutes as viable alternatives across all fracture complexities, challenging the traditional gold standard approach and offering particular benefits in resource-limited settings.
Publish Date 2025-09-10 07:53
Citation <p>Alshahrani AS, Alalwani YJ, Alqahtani NM, Alanazi ASD, Almarri AK, Alqurashi SS, Ghazi DK, Alsalamah AM, Alruwaili RH, Azzam AY, Alanii F. Outcomes of autologous bone grafts vs bone substitutes in tibial plateau fractures: A meta-analysis. <i>World J Orthop</i> 2025; 16(9): 111068</p>
URL https://www.wjgnet.com/2218-5836/full/v16/i9/111068.htm
DOI https://dx.doi.org/10.5312/wjo.v16.i9.111068
Full Article (PDF) WJO-16-111068-with-cover.pdf
PRISMA 2009 Checklist 111068-PRISMA-2009-Checklist.pdf
Manuscript File 111068_Auto_Edited_034015.docx
Answering Reviewers 111068-answering-reviewers.pdf
Audio Core Tip 111068-audio.mp3
Biostatistics Review Certificate 111068-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111068-conflict-of-interest-statement.pdf
Copyright License Agreement 111068-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111068-non-native-speakers.pdf
Supplementary Material 111068-supplementary-material.pdf
Peer-review Report 111068-peer-reviews.pdf
Scientific Misconduct Check 111068-scientific-misconduct-check.png
Scientific Editor Work List 111068-scientific-editor-work-list.pdf
CrossCheck Report 111068-crosscheck-report.pdf