| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Endoscopic sleeve gastrectomy vs traditional bariatric surgery: A paradigm shift in managing metabolic dysfunction-associated steatohepatitis and cirrhosis?
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
David Jerez Diaz, Rishi Devaraja Vattikuti, Allison Janak, Anuroop Yekula, Priya Farooq, Asad Ullah, Truptesh H Kothari, Shivangi Kothari, Vivek Kaul and Patrick Twohig |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Patrick Twohig, Assistant Professor, FRCPC, MD, Department of Gastroenterology and Hepatology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14682, United States. patrick_twohig@urmc.rochester.edu |
| Key Words |
Obesity; Metabolic dysfunction-associated steatohepatitis; Liver cirrhosis; Endoscopic sleeve gastroplasty; Laparoscopic sleeve gastrectomy; Roux-en-Y gastric bypass |
| Core Tip |
Endoscopic sleeve gastroplasty (ESG) is an emerging minimally invasive option for obesity and metabolic dysfunction-associated steatohepatitis (MASH), particularly in patients with advanced liver disease who are poor surgical candidates. This review explores ESG’s potential to improve weight loss, insulin resistance, and hepatic markers, with fewer complications than traditional bariatric surgery, though current evidence remains preliminary. As the global burden of MASH grows, ESG may represent a safer, more accessible intervention, especially where liver transplantation is not feasible, while ongoing trials and individualized strategies continue to clarify its long-term role in liver care. |
| Publish Date |
2025-12-05 11:28 |
| Citation |
Jerez Diaz D, Vattikuti RD, Janak A, Yekula A, Farooq P, Ullah A, Kothari TH, Kothari S, Kaul V, Twohig P. Endoscopic sleeve gastrectomy vs traditional bariatric surgery: A paradigm shift in managing metabolic dysfunction-associated steatohepatitis and cirrhosis? World J Gastrointest Pharmacol Ther 2025; 16(4): 111074 |
| URL |
https://www.wjgnet.com/2150-5349/full/v16/i4/111074.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v16.i4.111074 |
