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Articles Published Processes
12/4/2025 6:40:47 AM | Browse: 50 | Download: 150
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Received |
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2025-06-26 11:26 |
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Peer-Review Started |
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2025-06-26 11:26 |
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First Decision by Editorial Office Director |
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2025-07-08 07:02 |
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Return for Revision |
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2025-07-08 07:02 |
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Revised |
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2025-07-16 06:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-27 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-27 10:09 |
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Articles in Press |
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2025-10-27 10:09 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-02 00:57 |
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Publish the Manuscript Online |
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2025-12-04 06:40 |
| ISSN |
1949-8454 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Basic Study |
| Article Title |
Dithiothreitol induced endoplasmic reticulum stress and its role in neurodegeneration in Caenorhabditis elegans
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Govind Raj, Manish Kumar, Smriti Shreya, Shikha Bhardwaj, Ratna Priya, Kailash C Mangalhara and Buddhi Prakash Jain |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Buddhi Prakash Jain, Assistant Professor, Gene Expression and Signaling Lab, Department of Zoology, Mahatma Gandhi Central University, MGCUB MOTIHARI, Motihari 845401, Bihar, India. buddhiprakash@mgcub.ac.in |
| Key Words |
Behavioral assay; Caenorhabditis elegans; Dithiothreitol toxicity; Endoplasmic reticulum stress; Neurodegeneration |
| Core Tip |
Disturbancein the Protein folding process induces Endoplasmic Reticulum Stress and sueseqeunct activation of unfolded Protein Response. accumulation of misfolded or unfolded proteins has been reported in the pathogenesis of several neurodegenerative diseases. Dithiothreitol (DTT), a potent endoplasmic reticulum stress inducer might involve in neurodegenration and related disorders. The present work aims to study the effects of DTT on the unfolded protein response activation and neurobehavioural effects in the Caenorhabditis elegans. |
| Publish Date |
2025-12-04 06:40 |
| Citation |
Raj G, Kumar M, Shreya S, Bhardwaj S, Priya R, Mangalhara KC, Jain BP. Dithiothreitol induced endoplasmic reticulum stress and its role in neurodegeneration in Caenorhabditis elegans. World J Biol Chem 2025; 16(4): 111110 |
| URL |
https://www.wjgnet.com/1949-8454/full/v16/i4/111110.htm |
| DOI |
https://dx.doi.org/10.4331/wjbc.v16.i4.111110 |
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