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Articles Published Processes
2/28/2026 7:48:43 AM | Browse: 3 | Download: 7
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Received |
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2025-06-24 08:54 |
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Peer-Review Started |
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2025-06-24 08:54 |
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First Decision by Editorial Office Director |
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2025-07-21 08:39 |
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Return for Revision |
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2025-07-21 08:39 |
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Revised |
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2025-08-14 08:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-14 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-14 08:25 |
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Articles in Press |
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2025-11-14 08:25 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-09 01:02 |
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Publish the Manuscript Online |
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2026-02-28 07:48 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Burden and impact of acute kidney injury in acute liver failure: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Armin Ahmed, Medhavi Gautam, Afzal Azim, Banadana Chakravarti and Meenakshi Tiwari |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Armin Ahmed, Critical Care Medicine, King George's Medical University, Chowk, Lucknow 226003, Uttar Pradesh, India. drarminahmed@gmail.com |
| Key Words |
Acute liver failure; Acute kidney injury; Systematic review; Paracetamol related acute liver failure; Transient kidney injury; Persistent kidney injury |
| Core Tip |
This systematic review of nine studies (6031 patients) found that acute kidney injury (AKI) occurs in 62.9% of acute liver failure (ALF) cases, with incidence varying from 37.9% to 79.1%. Drug-induced ALF, especially paracetamol-related, was the predominant etiology in most cohorts, while viral hepatitis was more common in Asia. Few studies identified independent AKI risk factors, with systemic inflammation, shock, and tumor necrosis factor-alpha elevation among them. AKI was consistently associated with increased mortality and lower transplant-free survival. Significant gaps include a lack of etiological data, pathophysiological insights, and representation from low- and middle-income countries, highlighting the need for standardized definitions and multicenter research. |
| Publish Date |
2026-02-28 07:48 |
| Citation |
Ahmed A, Gautam M, Azim A, Chakravarti B, Tiwari M. Burden and impact of acute kidney injury in acute liver failure: A systematic review. World J Crit Care Med 2026; 15(1): 111114 |
| URL |
https://www.wjgnet.com/2220-3141/full/v15/i1/111114.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v15.i1.111114 |
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