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11/17/2025 3:52:05 AM | Browse: 13 | Download: 27
Publication Name World Journal of Immunology
Manuscript ID 111119
Country Indonesia
Received
2025-06-24 12:08
Peer-Review Started
2025-06-25 00:35
First Decision by Editorial Office Director
2025-07-02 02:56
Return for Revision
2025-07-02 02:56
Revised
2025-07-03 07:21
Publication Fee Transferred
Second Decision by Editor
2025-10-28 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-29 02:41
Articles in Press
2025-10-29 02:41
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-06 00:23
Publish the Manuscript Online
2025-11-17 03:52
ISSN 2219-2824 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Allergy
Manuscript Type Prospective Study
Article Title Role of IgE cells in the exacerbation and management of asthma: An experimental study
Manuscript Source Invited Manuscript
All Author List Agussalim Agussalim, Citrawati Citrawati and Adriyani Adam
ORCID
Author(s) ORCID Number
Agussalim Agussalim http://orcid.org/0000-0003-1822-5390
Funding Agency and Grant Number
Corresponding Author Agussalim Agussalim, Associate Professor, PhD, Department of Nursing, Makassar Health Polytechnic, Jalan Banta Bantaeng, Makassar city, Makassar 92152, Sulawesi Selatan, Indonesia. salim170878@gmail.com
Key Words Asthma; IgE; Allergic inflammation; Anti-IgE therapy; Experimental study
Core Tip Asthma is a chronic respiratory disease driven in part by immune mechanisms involving IgE. This experimental study highlights the significant role of IgE in asthma exacerbation and demonstrates that anti-IgE therapy—specifically with omalizumab—can markedly reduce IgE levels, improve lung function, enhance asthma control, and decrease the frequency of exacerbations. These findings emphasize the clinical value of incorporating immunomodulatory strategies, particularly targeted anti-IgE interventions, into the treatment of moderate to severe allergic asthma.
Publish Date 2025-11-17 03:52
Citation

Agussalim A, Citrawati C, Adam A. Role of IgE cells in the exacerbation and management of asthma: An experimental study. World J Immunol 2025; 15(1): 111119

URL https://www.wjgnet.com/2219-2824/full/v15/i1/111119.htm
DOI https://dx.doi.org/10.5411/wji.v15.i1.111119
Full Article (PDF) WJI-15-111119-with-cover.pdf
CONSORT 2010 Statement 111119-CONSORT-2010-statement.pdf
Manuscript File 111119_Auto_Edited_021019.docx
Answering Reviewers 111119-answering-reviewers.pdf
Audio Core Tip 111119-audio.mpeg
Biostatistics Review Certificate 111119-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111119-conflict-of-interest-statement.pdf
Copyright License Agreement 111119-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111119-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111119-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111119-non-native-speakers.pdf
Peer-review Report 111119-peer-reviews.pdf
Scientific Misconduct Check 111119-scientific-misconduct-check.png
Scientific Editor Work List 111119-scientific-editor-work-list.pdf
CrossCheck Report 111119-crosscheck-report.pdf