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Articles Published Processes
9/25/2025 11:24:04 AM | Browse: 99 | Download: 121
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Received |
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2025-06-24 08:31 |
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Peer-Review Started |
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2025-06-24 08:31 |
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First Decision by Editorial Office Director |
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2025-07-02 03:54 |
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Return for Revision |
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2025-07-02 03:54 |
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Revised |
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2025-07-10 21:15 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-08-21 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-21 03:41 |
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Articles in Press |
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2025-08-21 03:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-17 06:46 |
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Publish the Manuscript Online |
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2025-09-25 11:24 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Explant-based prognostic models for hepatocellular carcinoma recurrence after liver transplantation: A systematic review and meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Iago Christofoli de Barros, Matheus Vanzin Fernandes, Santiago Rodríguez Villafuerte and Ajacio Bandeira de Mello Brandão |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Santiago Rodríguez Villafuerte, Associate Professor, PhD, Directorate of Postgraduate Studies in Health Sciences, Universidad de las Américas, Vía a Nayón, Quito 170124, Pichincha, Ecuador. santy_rodri03@yahoo.com |
| Key Words |
Risk factors score; Liver transplantation; Hepatocellular carcinoma; Neoplasm recurrence; Local |
| Core Tip |
This systematic review and meta-analysis assessed the prognostic accuracy of three explant-based models-Risk Estimation of Tumor Recurrence after Transplant (RETREAT), Decaens, and Predicting Cancer Recurrence Score-in predicting hepatocellular carcinoma recurrence after liver transplantation. Analyzing nine retrospective studies with 5348 patients, recurrence was 7%, with no significant differences in area under the curve among models. While RETREAT is the most validated, all models demonstrated limited sensitivity, risking underestimation of recurrence risk. The findings highlight the need for improved prognostic tools, potentially through incorporating larger, prospective datasets and artificial intelligence, to enhance risk stratification, guide post-transplant surveillance, and optimize patient outcomes. |
| Publish Date |
2025-09-25 11:24 |
| Citation |
Christofoli de Barros I, Vanzin Fernandes M, Rodríguez Villafuerte S, Brandão ABM. Explant-based prognostic models for hepatocellular carcinoma recurrence after liver transplantation: A systematic review and meta-analysis. World J Hepatol 2025; 17(9): 111126 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i9/111126.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i9.111126 |
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