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Articles Published Processes
11/12/2025 9:50:41 AM | Browse: 59 | Download: 184
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Received |
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2025-06-24 08:36 |
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Peer-Review Started |
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2025-06-24 08:37 |
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First Decision by Editorial Office Director |
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2025-06-30 06:42 |
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Return for Revision |
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2025-06-30 06:42 |
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Revised |
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2025-07-07 11:19 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-11 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-11 08:14 |
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Articles in Press |
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2025-10-11 08:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-31 13:25 |
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Publish the Manuscript Online |
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2025-11-12 09:50 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Review |
| Article Title |
Beyond the optic disc: Investigating gender-based differences in optic neuritis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Zeppieri, Simonetta Gaia Nicolosi, Fabiana D’Esposito, Mutali Musa, Alessandro Avitabile, Caterina Gagliano, Marco Battista, Piero Barboni and Matteo Capobianco |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Zeppieri, MD, PhD, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Optic neuritis; Gender differences; Neuromyelitis optica spectrum disorder; Myelin oligodendrocyte glycoprotein antibody disease; Optic nerve |
| Core Tip |
Optic neuritis (ON) is affected by sex at all levels, from molecular biology to clinical outcomes. Women are considerably more predisposed to developing ON, particularly in aquaporin 4 IgG positive neuromyelitis optica spectrum disorder. Men frequently experience more severe long-term neuroaxonal damage. The interaction of genetic, hormonal, metabolic, and behavioral variables highlights the necessity for sex-specific strategies in the diagnosis, treatment, and research of ON. Comprehending these distinctions is crucial for enhancing individualized treatment in ON across various demyelinating conditions. |
| Publish Date |
2025-11-12 09:50 |
| Citation |
Zeppieri M, Nicolosi SG, D’Esposito F, Musa M, Avitabile A, Gagliano C, Battista M, Barboni P, Capobianco M. Beyond the optic disc: Investigating gender-based differences in optic neuritis. World J Clin Cases 2025; 13(32): 111134 |
| URL |
https://www.wjgnet.com/2307-8960/full/v13/i32/111134.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v13.i32.111134 |
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