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11/25/2025 11:05:36 AM | Browse: 46 | Download: 212
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 111138
Country China
Received
2025-07-15 09:30
Peer-Review Started
2025-07-15 09:30
First Decision by Editorial Office Director
2025-08-06 08:36
Return for Revision
2025-08-06 08:36
Revised
2025-08-19 14:34
Publication Fee Transferred
2025-08-26 06:25
Second Decision by Editor
2025-09-25 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-25 03:35
Articles in Press
2025-09-25 03:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-07 03:46
Publish the Manuscript Online
2025-11-25 11:05
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Impact of primary colorectal cancer site on surgical outcomes for liver metastases: A retrospective study
Manuscript Source Unsolicited Manuscript
All Author List Da-Mao Liu, Xian-Yu Yang, Hui-Hua Zheng, Pan-Min Chen, Shu-Kun Zeng and Yu-Feng Wei
ORCID
Author(s) ORCID Number
Yu-Feng Wei http://orcid.org/0009-0004-1182-9583
Funding Agency and Grant Number
Corresponding Author Yu-Feng Wei, MD, Department of General Surgery, The Affiliated Hospital of Jiangxi University of Chinese Medicine, No. 445 Bayi Avenue, Donghu District, Nanchang 330200, Jiangxi Province, China. wy18070036305@163.com
Key Words Colorectal cancer; Tumor metastasis; Liver tumor recurrence; Resection of metastatic tumor; D-dimer; Risk assessment
Core Tip This retrospective study investigates how the primary tumor location in colorectal cancer affects clinical outcomes following liver metastasis resection. Among 178 patients, right-sided colon cancers were associated with significantly higher recurrence rates, postoperative complications, and worse survival compared to left-sided and rectal cancers. Multivariate analysis identified right-sided origin, lymph node metastasis, elevated D-dimer, hypoalbuminemia, poor neoadjuvant response, and high clinical risk scores as independent predictors of recurrence. These findings highlight the prognostic importance of tumor site and support site-specific treatment strategies for patients with colorectal liver metastases to improve surgical safety and long-term outcomes.
Publish Date 2025-11-25 11:05
Citation

Liu DM, Yang XY, Zheng HH, Chen PM, Zeng SK, Wei YF. Impact of primary colorectal cancer site on surgical outcomes for liver metastases: A retrospective study. World J Gastrointest Surg 2025; 17(11): 111138

URL https://www.wjgnet.com/1948-9366/full/v17/i11/111138.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i11.111138
Full Article (PDF) WJGS-17-111138-with-cover.pdf
Manuscript File 111138_Auto_Edited_061825.docx
Answering Reviewers 111138-answering-reviewers.pdf
Audio Core Tip 111138-audio.mp3
Biostatistics Review Certificate 111138-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111138-conflict-of-interest-statement.pdf
Copyright License Agreement 111138-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111138-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111138-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111138-non-native-speakers.pdf
Peer-review Report 111138-peer-reviews.pdf
Scientific Misconduct Check 111138-scientific-misconduct-check.png
Scientific Editor Work List 111138-scientific-editor-work-list.pdf
CrossCheck Report 111138-crosscheck-report.pdf