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Articles Published Processes
1/14/2026 8:09:15 AM | Browse: 70 | Download: 252
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Received |
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2025-06-25 01:53 |
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Peer-Review Started |
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2025-06-25 09:19 |
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First Decision by Editorial Office Director |
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2025-07-11 07:44 |
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Return for Revision |
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2025-07-11 07:44 |
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Revised |
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2025-07-21 14:56 |
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Publication Fee Transferred |
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2025-07-23 09:10 |
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Second Decision by Editor |
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2025-10-15 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-02 07:26 |
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Articles in Press |
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2025-12-02 07:26 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-04 00:24 |
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Publish the Manuscript Online |
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2026-01-14 08:09 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Endothelial cell-derived exosomes inhibit high glucose-induced osteoblast ferroptosis by activating microRNA-335-3p/prostaglandin endoperoxide synthase 2
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chen Shao, Li-Jian Zhang, Yi-Lin Song, Yan-Qiu Wang, Xiu-Jing Zha, Juan Li, Cheng-Song Ye, Ling-Ling Chen, Ming-Wei Chen and Guo-Xi Jin |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Projects of Bengbu Medical College |
2022byzd088 |
| Anhui Province Higher Education Scientific Research Project |
2024AH051285 |
| Anhui Provincial Department of Education Humanities and Social Science Key Project |
2023AH051900 |
| Key Research and Development Program Projects of Anhui Province |
202204295107020049 |
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| Corresponding Author |
Guo-Xi Jin, Chief Physician, PhD, Professor, Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical University, No. 287 Changhuai Road, Bengbu 233004, Anhui Province, China. jinguoxi@bbmu.edu.cn |
| Key Words |
Type 2 diabetes; Osteoporosis; Exosomes; Ferroptosis; Oxidative stress |
| Core Tip |
Endothelial cell-derived exosomes demonstrate inherent bone-targeting properties, their role in counteracting high glucose-induced osteoblast ferroptosis remains unexplored. This study reveals that endothelial cell-derived exosomes protect osteoblasts from high glucose-induced ferroptosis by regulating microRNA-335-3p/prostaglandin endoperoxide synthase 2. The diagnostic potential of serum microRNA-335-3p for diabetic osteoporosis was demonstrated, warranting further validation with an expanded sample size. |
| Publish Date |
2026-01-14 08:09 |
| Citation |
Shao C, Zhang LJ, Song YL, Wang YQ, Zha XJ, Li J, Ye CS, Chen LL, Chen MW, Jin GX. Endothelial cell-derived exosomes inhibit high glucose-induced osteoblast ferroptosis by activating microRNA-335-3p/prostaglandin endoperoxide synthase 2. World J Diabetes 2026; 17(1): 111165 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i1/111165.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i1.111165 |
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