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Articles Published Processes
11/14/2025 12:56:13 AM | Browse: 107 | Download: 385
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Received |
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2025-06-25 06:47 |
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Peer-Review Started |
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2025-06-25 06:48 |
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First Decision by Editorial Office Director |
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2025-08-14 08:48 |
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Return for Revision |
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2025-08-15 04:05 |
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Revised |
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2025-08-27 17:34 |
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Publication Fee Transferred |
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2025-08-28 13:42 |
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Second Decision by Editor |
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2025-09-28 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-28 10:45 |
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Articles in Press |
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2025-09-28 10:45 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-05 00:55 |
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Publish the Manuscript Online |
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2025-11-14 00:56 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Tumour chemotherapy sensitivity test may predict clinical outcomes in colorectal cancer patients receiving oxaliplatin and fluoropyrimidine-based regimens
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Si-Jia Li, Yi-Xuan Lu, Fang-Yue Zheng, Yi-Cong Bian, Li-Yan Miao and Chen-Rong Huang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
U24A20765, T2321005 |
| Jiangsu Provincial Science and Technology Plan Special Fund |
BM2023003 |
| Jiangsu Provincial Medical Key Discipline |
ZDXK202247 |
| Priority Academic Program Development of the Jiangsu Higher Education Institutes |
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| Jiangsu Engineering Research Center on Drug Evaluation and Translation of Organoids/Organ Chip (2024) |
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| Science and Technology Plan of Suzhou |
SKYD2023183 |
| Research Project Established by Chinese Pharmaceutical Association Hospital Pharmacy Department |
CPA-Z05-ZC-2023002 |
| Gusu Health Talent Research Project |
GSWS2022015 |
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| Corresponding Author |
Chen-Rong Huang, PhD, Department of Pharmacy, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Suzhou 215006, Jiangsu Province, China. huangchenrong@suda.edu.cn |
| Key Words |
Colorectal cancer; Precision oncology; Adenosine triphosphate-based tumour chemotherapy sensitivity test; Clinical prediction model; Chemosensitivity; 5-fluorouracil; Oxaliplatin |
| Core Tip |
In this study, retrospectively evaluated the clinical application of adenosine triphosphate-based tumour chemotherapy sensitivity test (ATP-TCA) and revealed that it is an independent prognostic factor for disease-free survival in patients with resectable colorectal cancer. Additionally, an ATP-TCA-sensitive chemotherapy regimen was shown to significantly improve overall survival and disease-free survival in colorectal patients in stage III. Although the necessity for further validation, this study provides evidence supporting the extension of ATP-TCA assays to combination chemotherapy regimens for colorectal cancer while providing a theoretical basis and perspective for future advancements in personalized medicine. |
| Publish Date |
2025-11-14 00:56 |
| Citation |
Li SJ, Lu YX, Zheng FY, Bian YC, Miao LY, Huang CR. Tumour chemotherapy sensitivity test may predict clinical outcomes in colorectal cancer patients receiving oxaliplatin and fluoropyrimidine-based regimens. World J Gastrointest Oncol 2025; 17(11): 111171 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i11/111171.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i11.111171 |
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