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12/10/2025 7:48:09 AM | Browse: 3 | Download: 6
Publication Name World Journal of Gastroenterology
Manuscript ID 111176
Country China
Received
2025-06-30 09:27
Peer-Review Started
2025-06-30 09:27
First Decision by Editorial Office Director
2025-08-06 11:45
Return for Revision
2025-08-06 11:45
Revised
2025-08-31 08:28
Publication Fee Transferred
Second Decision by Editor
2025-10-21 02:53
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-21 06:41
Articles in Press
2025-10-21 06:41
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-30 10:32
Publish the Manuscript Online
2025-12-10 07:48
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Artificial intelligence in hepatopathy diagnosis and treatment: Big data analytics, deep learning, and clinical prediction models
Manuscript Source Invited Manuscript
All Author List Jing-Ran Sun, Xiao-Ning Sun, Bing-Jiu Lu and Bao-Cheng Deng
ORCID
Author(s) ORCID Number
Bao-Cheng Deng http://orcid.org/0000-0003-4825-9794
Funding Agency and Grant Number
Funding Agency Grant Number
Science Planning Project of Liaoning Province 2019JH2/10300031-05
National Natural Science Foundation of China 12171074
Corresponding Author Bao-Cheng Deng, PhD, The Second Department of Infectious Diseases, The First Affiliated Hospital, China Medical University, No. 155 Nanjing North Street, Shenyang 110001, Liaoning Province, China. sydengbc@163.com
Key Words Artificial intelligence; Hepatology; Liver disease diagnosis; Deep learning; Clinical prediction models
Core Tip This review highlights how artificial intelligence is transforming hepatology by enabling early diagnosis, fibrosis staging, hepatocellular carcinoma detection, and personalized treatment. Key innovations include deep learning for imaging, multi-omics integration, and privacy-preserving federated learning. Explainable artificial intelligence builds clinician trust. Despite promising results, challenges like data heterogeneity, regulatory barriers, and limited real-time integration remain. Continued efforts in validation, ethical oversight, and user-centered design are essential for clinical adoption.
Publish Date 2025-12-10 07:48
Citation

Sun JR, Sun XN, Lu BJ, Deng BC. Artificial intelligence in hepatopathy diagnosis and treatment: Big data analytics, deep learning, and clinical prediction models. World J Gastroenterol 2025; 31(46): 111176

URL https://www.wjgnet.com/1007-9327/full/v31/i46/111176.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i46.111176
Manuscript File 111176_Auto_Edited_023517.docx
Answering Reviewers 111176-answering-reviewers.pdf
Audio Core Tip 111176-audio.mp3
Conflict-of-Interest Disclosure Form 111176-conflict-of-interest-statement.pdf
Copyright License Agreement 111176-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111176-non-native-speakers.pdf
Peer-review Report 111176-peer-reviews.pdf
Scientific Misconduct Check 111176-scientific-misconduct-check.png
Scientific Editor Work List 111176-scientific-editor-work-list.pdf
CrossCheck Report 111176-crosscheck-report.pdf