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1/30/2026 6:45:46 AM | Browse: 3 | Download: 1
Publication Name World Journal of Psychiatry
Manuscript ID 111196
Country China
Received
2025-08-26 09:16
Peer-Review Started
2025-08-26 09:16
First Decision by Editorial Office Director
2025-09-16 07:27
Return for Revision
2025-09-16 07:27
Revised
2025-10-15 06:03
Publication Fee Transferred
2025-10-17 03:50
Second Decision by Editor
2025-11-10 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-10 07:23
Articles in Press
2025-11-10 07:23
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-18 03:42
Publish the Manuscript Online
2026-01-30 06:45
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology
Manuscript Type Observational Study
Article Title Correlation of anxiety/depression status with stress-related markers and cancer-related fatigue in patients with colon cancer
Manuscript Source Unsolicited Manuscript
All Author List Ling Zhao, Bin Jian and Duan-Hong Chen
ORCID
Author(s) ORCID Number
Duan-Hong Chen http://orcid.org/0009-0004-8358-0035
Funding Agency and Grant Number
Corresponding Author Duan-Hong Chen, Department of Traditional Chinese Medicine, The Affiliated Yongchuan Hospital of Chongqing Medical University, No. 439, Xuanhua Road, Yongchuan District, Chongqing 402160, China. chenduanhong1986@163.com
Key Words Colon cancer; Anxiety; Depression; Stress-related markers; Cancer-related fatigue
Core Tip Focusing on patients with colon cancer (CC; n = 120), this study comprehensively explored psychological and clinical correlates. Results indicated anxiety/depression in over 50% of patients with CC, with symptoms primarily falling into the mild category. Notably, anxiety and depression correlated significantly and positively with stress-related factors (heat shock protein 70 and C-reactive protein) and cancer-induced fatigue. Moreover, certain clinical features—specifically being female, being 60 years old or older, and having a stage III or IV tumor—were confirmed to increase the risk of patients with CC to developing anxiety or depression. These results offer valuable evidence-based support for clinical practice, such as screening for psychological distress, classifying patients by risk level, and implementing tailored psychological support for patients with CC.
Publish Date 2026-01-30 06:45
Citation

Zhao L, Jian B, Chen DH. Correlation of anxiety/depression status with stress-related markers and cancer-related fatigue in patients with colon cancer. World J Psychiatry 2026; 16(2): 111196

URL https://www.wjgnet.com/2220-3206/full/v16/i2/111196.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i2.111196
Full Article (PDF) WJP-16-111196-with-cover.pdf
STROBE Statement 111196-STROBE-statement.pdf
Manuscript File 111196_Auto_Edited_022333.docx
Answering Reviewers 111196-answering-reviewers.pdf
Audio Core Tip 111196-audio.mp3
Biostatistics Review Certificate 111196-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111196-conflict-of-interest-statement.pdf
Copyright License Agreement 111196-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111196-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111196-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111196-non-native-speakers.pdf
Peer-review Report 111196-peer-reviews.pdf
Scientific Misconduct Check 111196-scientific-misconduct-check.png
Scientific Editor Work List 111196-scientific-editor-work-list.pdf
CrossCheck Report 111196-crosscheck-report.pdf