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3/15/2026 6:11:26 AM | Browse: 11 | Download: 13
Publication Name World Journal of Experimental Medicine
Manuscript ID 111197
Country Poland
Received
2025-06-25 06:31
Peer-Review Started
2025-06-25 06:31
First Decision by Editorial Office Director
2025-07-03 11:01
Return for Revision
2025-07-03 11:01
Revised
2025-08-04 09:47
Publication Fee Transferred
Second Decision by Editor
2026-01-05 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-05 11:31
Articles in Press
2026-01-05 11:31
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-04 00:30
Publish the Manuscript Online
2026-03-15 06:11
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Observational Study
Article Title Correlation between heart rate variability and severity of coronary atherosclerosis: Looking for non-invasive indicators of the disease severity
Manuscript Source Invited Manuscript
All Author List Michal Kuzemczak, Izabela Miechowicz, Rafal Januszek and Tomasz Siminiak
ORCID
Author(s) ORCID Number
Michal Kuzemczak http://orcid.org/0000-0003-0453-642X
Funding Agency and Grant Number
Corresponding Author Michal Kuzemczak, Assistant Professor, MD, PhD, Division of Emergency Medicine, Poznan University of Medical Sciences, Rokietnicka 7 Street, Poznan 60-806, Poland. michal.kuzemczak@gmail.com
Key Words Heart rate variability; Ischemic heart disease; Gensini score; Coronary atherosclerosis; Gensini score
Core Tip This study explores the relationship between heart rate variability (HRV) and angiographic severity of ischemic heart disease as reflected by the Gensini score. While traditional HRV indices (standard deviation of NN intervals, root mean square of successive differences, spectral indices) showed no significant correlations, several novel parameters - including de Hann sinus tachycardia index, van Geijn interbeat interval difference, Huey long-term variability, and Dalton mean absolute beat-to-beat - demonstrated weak but statistically significant associations. These findings highlight the potential value of emerging HRV indices in assessing coronary atherosclerosis severity and suggest new directions for research in noninvasive cardiac risk stratification in stable ischemic heart disease patients.
Publish Date 2026-03-15 06:11
Citation

Kuzemczak M, Miechowicz I, Januszek R, Siminiak T. Correlation between heart rate variability and severity of coronary atherosclerosis: Looking for non-invasive indicators of the disease severity. World J Exp Med 2026; 16(1): 111197

URL https://www.wjgnet.com/2220-315x/full/v16/i1/111197.htm
DOI https://dx.doi.org/10.5493/wjem.v16.i1.111197
Full Article (PDF) WJEM-16-111197-with-cover.pdf
STROBE Statement 111197-STROBE-statement.pdf
Manuscript File 111197_Auto_Edited_090327.docx
Answering Reviewers 111197-answering-reviewers.pdf
Audio Core Tip 111197-audio.m4a
Biostatistics Review Certificate 111197-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111197-conflict-of-interest-statement.pdf
Copyright License Agreement 111197-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111197-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111197-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111197-non-native-speakers.pdf
Peer-review Report 111197-peer-reviews.pdf
Scientific Misconduct Check 111197-scientific-misconduct-check.png
Scientific Editor Work List 111197-scientific-editor-work-list.pdf
CrossCheck Report 111197-crosscheck-report.pdf