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10/14/2025 7:41:42 AM | Browse: 9 | Download: 38
Publication Name World Journal of Gastroenterology
Manuscript ID 111210
Country United States
Received
2025-06-26 08:14
Peer-Review Started
2025-06-26 08:18
To Make the First Decision
Return for Revision
2025-07-21 08:58
Revised
2025-07-29 00:32
Second Decision
2025-09-01 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-01 05:33
Articles in Press
2025-09-01 05:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-25 01:56
Publish the Manuscript Online
2025-10-14 07:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Oral microbiome and inflammatory bowel disease: New understanding and call to action
Manuscript Source Invited Manuscript
All Author List Michael Saadeh, Sydney Donohue, Shaina Ailawadi, Gordon Hong and David A Johnson
ORCID
Author(s) ORCID Number
Michael Saadeh http://orcid.org/0000-0001-9314-5361
David A Johnson http://orcid.org/0000-0002-8737-0711
Funding Agency and Grant Number
Corresponding Author David A Johnson, FACG, FACP, FASGE, Full Professor, MD, Division of Gastroenterology, Department of Internal Medicine, Eastern Virginia Medical School, 886 Kempsville Road Suite 114, Norfolk, VA 23507, United States. dajevms@aol.com
Key Words Inflammatory bowel disease; Oral microbiome; Dysbiosis; Periodontitis; Crohn’s disease; Ulcerative colitis; Inflammation
Core Tip The oral microbiome, traditionally studied in the context of dental disease, is now recognized as a key player in systemic inflammation, including inflammatory bowel disease (IBD). This minireview outlines emerging evidence of shared microbial signatures, immune pathways, and pathogenic mechanisms between the oral cavity and gut in IBD. We highlight diagnostic and therapeutic opportunities targeting oral dysbiosis, including oral probiotics, dental hygiene, and periodontal therapy, as novel adjuncts to IBD management. Greater integration of oral health into IBD management may offer a more comprehensive and personalized treatment approach.
Publish Date 2025-10-14 07:41
Citation <p>Saadeh M, Donohue S, Ailawadi S, Hong G, Johnson DA. Oral microbiome and inflammatory bowel disease: New understanding and call to action. <i>World J Gastroenterol</i> 2025; 31(38): 111210</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i38/111210.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i38.111210
Full Article (PDF) WJG-31-111210-with-cover.pdf
Manuscript File 111210_Auto_Edited_083719.docx
Answering Reviewers 111210-answering-reviewers.pdf
Audio Core Tip 111210-audio.mp3
Conflict-of-Interest Disclosure Form 111210-conflict-of-interest-statement.pdf
Copyright License Agreement 111210-copyright-assignment.pdf
Peer-review Report 111210-peer-reviews.pdf
Scientific Misconduct Check 111210-scientific-misconduct-check.png
Scientific Editor Work List 111210-scientific-editor-work-list.pdf
CrossCheck Report 111210-crosscheck-report.pdf