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Articles Published Processes
1/27/2026 10:12:30 AM | Browse: 53 | Download: 139
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Received |
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2025-06-26 08:22 |
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Peer-Review Started |
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2025-06-26 08:26 |
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First Decision by Editorial Office Director |
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2025-07-21 09:00 |
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Return for Revision |
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2025-07-21 13:37 |
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Revised |
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2025-09-02 09:06 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-01 03:10 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-02 06:09 |
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Articles in Press |
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2025-12-02 06:09 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-13 03:40 |
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Publish the Manuscript Online |
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2026-01-27 10:12 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Minireviews |
| Article Title |
Fighting the epidemic of pediatric metabolic dysfunction-associated steatotic liver disease: Role of non-invasive diagnostics and early pharmacological intervention
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nicholas Beng-Hui Ng, Andrew Anjian SNG and James Guoxian Huang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
James Guoxian Huang, Assistant Professor, Khoo Teck Puat - National University Children's Medical Institute, Department of Paediatrics, National University Health System, 1E Kent Ridge Road
NUHS Tower Block Level 12, Singapore 119228, Singapore. paehgj@nus.edu.sg |
| Key Words |
Pediatric metabolic dysfunction-associated steatotic liver disease; Glucagon-like peptide 1 receptor agonists; Vibration-controlled transient elastography; Resmetirom; Pediatric obesity |
| Core Tip |
The escalating prevalence of pediatric metabolic dysfunction-associated steatotic liver disease (MASLD) mirrors the rise in pediatric obesity. The advent of non-invasive diagnostics may allow for earlier recognition of liver fibrosis, and may prioritize the need for early pharmacological therapy. We propose an updated diagnostic and monitoring algorithm incorporating recent multi-societal statements in pediatric MASLD. The increased use of weight-loss pharmacotherapy such as glucagon-like peptide 1 receptor agonists in adolescent patients has shown efficacy in inducing weight loss, which may have potential in halting MASLD progression if instituted early in the disease course. |
| Publish Date |
2026-01-27 10:12 |
| Citation |
Ng NBH, SNG AA, Huang JG. Fighting the epidemic of pediatric metabolic dysfunction-associated steatotic liver disease: Role of non-invasive diagnostics and early pharmacological intervention. World J Hepatol 2026; 18(1): 111211 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i1/111211.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i1.111211 |
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