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Articles Published Processes
10/24/2025 6:10:14 AM | Browse: 106 | Download: 403
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Received |
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2025-06-26 11:14 |
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Peer-Review Started |
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2025-06-26 11:14 |
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First Decision by Editorial Office Director |
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2025-07-31 07:59 |
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Return for Revision |
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2025-07-31 07:59 |
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Revised |
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2025-08-04 02:13 |
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Publication Fee Transferred |
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2025-08-05 01:54 |
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Second Decision by Editor |
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2025-09-25 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-25 07:33 |
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Articles in Press |
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2025-09-25 07:33 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-17 08:21 |
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Publish the Manuscript Online |
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2025-10-24 06:10 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Laboratory Technology |
| Manuscript Type |
Basic Study |
| Article Title |
Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Shi, Wen-Li Sai, Jin-Liang Chen, Li-Wei Qiu, Min Yao, Jun Zhao and Deng-Fu Yao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangsu Commission of Health of China |
M2020096 |
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| Corresponding Author |
Deng-Fu Yao, MD, PhD, Postdoc, Professor, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, No. 20 West Temple Road, Nantong 226001, Jiangsu Province, China. yaodf@ahnmc.com |
| Key Words |
Targeted therapy; Xenograft growth; Biological behaviors; Diagnostic biomarker; Lung adenocarcinoma; Lung squamous-cell carcinoma; Lung cancer; Oncogenic Krüppel-like factor-5 |
| Core Tip |
Krüppel-like factor-5 (KLF5) is upregulated in lung cancer, with stronger expression in lung squamous-cell carcinoma (LUSC) than in lung adenocarcinoma. Upregulated KLF5 expression was associated with the proliferation, migration and cell cycle of lung cancer cells, which is likely a favorable diagnostic biomarker of LUSC and could be a new molecular target for lung cancer. Furthermore, KLF5 might exert its oncogenic regulatory effects on the growth of lung cancer by increasing metastasis or progression by activating related signaling pathways. |
| Publish Date |
2025-10-24 06:10 |
| Citation |
Shi Y, Sai WL, Chen JL, Qiu LW, Yao M, Zhao J, Yao DF. Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma. World J Clin Oncol 2025; 16(10): 111213 |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i10/111213.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i10.111213 |
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