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10/15/2025 9:03:26 AM | Browse: 9 | Download: 73
Publication Name World Journal of Diabetes
Manuscript ID 111230
Country United Kingdom
Received
2025-06-26 07:12
Peer-Review Started
2025-06-30 08:37
To Make the First Decision
Return for Revision
2025-08-08 07:57
Revised
2025-08-14 16:35
Second Decision
2025-09-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-15 10:26
Articles in Press
2025-09-15 10:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-09 01:29
Publish the Manuscript Online
2025-10-15 09:03
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Meta-Analysis
Article Title Role of automated insulin delivery in managing insulin-treated outpatients with type 2 diabetes: A systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Abul Bashar Mohammad Kamrul-Hasan, Joseph M Pappachan, Lakshmi Nagendra, Nazma Akter, Sweekruti Jena, Deep Dutta and Sunil Nair
ORCID
Author(s) ORCID Number
Abul Bashar Mohammad Kamrul-Hasan http://orcid.org/0000-0002-5681-6522
Joseph M Pappachan http://orcid.org/0000-0003-0886-5255
Lakshmi Nagendra http://orcid.org/0000-0001-6865-5554
Sweekruti Jena http://orcid.org/0000-0002-4278-1525
Deep Dutta http://orcid.org/0000-0003-4915-8805
Funding Agency and Grant Number
Corresponding Author Joseph M Pappachan, FRCP, MD, MRCP, Professor, Senior Researcher, Faculty of Science, Manchester Metropolitan University, Lower Ormond Street, Manchester M15 6BH, Greater Manchester, United Kingdom. drpappachan@yahoo.co.in
Key Words Automated insulin delivery; Type 2 diabetes; Time in range; Glycated hemoglobin; Meta-analysis
Core Tip This is the first systematic review and meta-analysis specifically targeting the efficacy and safety of automated insulin delivery (AID) systems in patients with type 2 diabetes in the outpatient setting. Analyzing six randomized controlled trials and nine single-arm studies involving 28985 participants, we observed that AID systems enhance glycemic control, evidenced by larger decreases in glycated hemoglobin and improved continuous glucose monitoring metrics compared to standard treatment. AID use increases time in range, reduces time above target glucose, and maintains similar rates of hypoglycemia and serious adverse events. While AID slightly increases the risk of device deficiency, safety is still within acceptable limits. The results indicate short-term effectiveness, but larger and longer-term studies are necessary to confirm the benefits and assess cost-effectiveness.
Publish Date 2025-10-15 09:03
Citation <p>Kamrul-Hasan ABM, Pappachan JM, Nagendra L, Akter N, Jena S, Dutta D, Nair S. Role of automated insulin delivery in managing insulin-treated outpatients with type 2 diabetes: A systematic review and meta-analysis. <i>World J Diabetes</i> 2025; 16(10): 111230</p>
URL https://www.wjgnet.com/1948-9358/full/v16/i10/111230.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i10.111230
Full Article (PDF) WJD-16-111230-with-cover.pdf
PRISMA 2009 Checklist 111230-PRISMA-2009-Checklist.pdf
Manuscript File 111230_Auto_Edited_095137.docx
Answering Reviewers 111230-answering-reviewers.pdf
Audio Core Tip 111230-audio.m4a
Biostatistics Review Certificate 111230-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111230-conflict-of-interest-statement.pdf
Copyright License Agreement 111230-copyright-assignment.pdf
Supplementary Material 111230-supplementary-material.pdf
Peer-review Report 111230-peer-reviews.pdf
Scientific Misconduct Check 111230-scientific-misconduct-check.docx
Scientific Editor Work List 111230-scientific-editor-work-list.pdf
CrossCheck Report 111230-crosscheck-report.pdf