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Articles Published Processes
12/22/2025 7:43:01 AM | Browse: 86 | Download: 443
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Received |
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2025-06-26 04:16 |
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Peer-Review Started |
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2025-06-26 04:17 |
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First Decision by Editorial Office Director |
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2025-07-01 09:48 |
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Return for Revision |
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2025-07-03 17:51 |
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Revised |
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2025-07-28 02:42 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-27 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-27 09:55 |
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Articles in Press |
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2025-10-27 09:55 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-15 03:45 |
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Publish the Manuscript Online |
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2025-12-22 07:43 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Guardians within: Cross-talk between the gut microbiome and host immune system
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nabanita Ghosh and Krishnendu Sinha |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nabanita Ghosh, PhD, Department of Zoology, Maulana Azad College, No. 8 Rafi Ahmed Kidwai Road, Kolkata 700013, India. nabanitaghosh89@gmail.com |
| Key Words |
Gut microbiome; Immune system; Microbiota-immune axis; Dysbiosis; Inflammation |
| Core Tip |
This review highlights the critical interplay between the gut microbiome and the host immune system, focusing on how gut microbes and their metabolites, such as short-chain fatty acids, influence immune cell development, inflammatory regulation, and immune homeostasis. It emphasizes recent advances in metagenomics, metabolomics, and single-cell sequencing that have uncovered novel mechanisms of microbiota-driven immune modulation. The discussion also addresses the microbiome’s role in early-life immune education and its implications for autoimmune diseases, inflammation, and cancer immunotherapy, offering insights into emerging microbiome-based therapeutic strategies. |
| Publish Date |
2025-12-22 07:43 |
| Citation |
Ghosh N, Sinha K. Guardians within: Cross-talk between the gut microbiome and host immune system. World J Gastrointest Pathophysiol 2025; 16(4): 111245 |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i4/111245.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i4.111245 |
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