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1/5/2026 6:55:13 AM | Browse: 6 | Download: 1
Publication Name World Journal of Clinical Cases
Manuscript ID 111246
Country Croatia
Received
2025-06-30 12:54
Peer-Review Started
2025-06-30 12:54
First Decision by Editorial Office Director
2025-07-19 01:50
Return for Revision
2025-07-19 01:50
Revised
2025-08-01 12:05
Publication Fee Transferred
Second Decision by Editor
2025-12-22 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-22 08:57
Articles in Press
2025-12-22 08:57
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-31 01:13
Publish the Manuscript Online
2026-01-05 06:55
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Minireviews
Article Title Unfolding the enigma of familial Hodgkin lymphoma: Current insights
Manuscript Source Invited Manuscript
All Author List Jelena Roganovic, Nusa Matijasic Stjepovic and Ana Dordevic
ORCID
Author(s) ORCID Number
Jelena Roganovic http://orcid.org/0000-0002-7960-6069
Nusa Matijasic Stjepovic http://orcid.org/0000-0002-1568-5095
Ana Dordevic http://orcid.org/0000-0003-3896-6698
Funding Agency and Grant Number
Corresponding Author Jelena Roganovic, MD, PhD, Tenured Professor, Department for Pediatric Oncology and Hematology, Children's Hospital Zagreb, Klaiceva 16, Zagreb 10000, Croatia. jelena.roganovic02@gmail.com
Key Words Hodgkin lymphoma; Familial Hodgkin lymphoma; Genetic analysis; Whole genome sequencing; Pathogenic variants
Core Tip Hodgkin lymphoma (HL), although rare, is one of the most common pediatric malignancies. Familial clustering points to genetic susceptibility, especially in young-onset cases. Recently, whole-genome sequencing studies of affected families have identified several predisposing genetic variants, contributing to unraveling the complex etiopathogenesis of HL. New insights into tumor biology and the identification of germline mutations may facilitate genetic counselling, raising awareness among first-degree relatives of HL patients about potential symptoms and leading to earlier diagnosis and better outcomes. Emphasizing that the hereditary risk of HL remains low can provide significant psychological relief for affected families.
Publish Date 2026-01-05 06:55
Citation

Roganovic J, Matijasic Stjepovic N, Dordevic A. Unfolding the enigma of familial Hodgkin lymphoma: Current insights. World J Clin Cases 2026; 14(1): 111246

URL https://www.wjgnet.com/2307-8960/full/v14/i1/111246.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i1.111246
Full Article (PDF) WJCC-14-111246-with-cover.pdf
Manuscript File 111246_Auto_Edited_080347.docx
Answering Reviewers 111246-answering-reviewers.pdf
Audio Core Tip 111246-audio.m4a
Conflict-of-Interest Disclosure Form 111246-conflict-of-interest-statement.pdf
Copyright License Agreement 111246-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111246-non-native-speakers.pdf
Peer-review Report 111246-peer-reviews.pdf
Scientific Misconduct Check 111246-scientific-misconduct-check.png
Scientific Editor Work List 111246-scientific-editor-work-list.pdf
CrossCheck Report 111246-crosscheck-report.pdf