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Articles Published Processes
11/14/2025 12:56:17 AM | Browse: 7 | Download: 36
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Received |
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2025-06-27 02:27 |
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Peer-Review Started |
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2025-06-27 02:27 |
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First Decision by Editorial Office Director |
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2025-07-02 02:23 |
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Return for Revision |
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2025-07-02 02:23 |
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Revised |
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2025-07-12 06:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-09 01:15 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-09 06:33 |
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Articles in Press |
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2025-10-09 06:33 |
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Edit the Manuscript by Language Editor |
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2025-10-13 17:56 |
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Typeset the Manuscript |
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2025-11-04 02:45 |
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Publish the Manuscript Online |
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2025-11-14 00:56 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Comparing early surgical outcomes between total neoadjuvant therapy and standard long course chemoradiotherapy for rectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Salman Ahmed Abdul Jabbar, Amadora Li En Choo, Neng-Wei Wong, James Chi-Yong Ngu and Nan-Zun Teo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nan-Zun Teo, Assistant Professor, Consultant, FRCS (Ed), Department of General Surgery, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. teo.nan.zun@singhealth.com.sg |
| Key Words |
Locally advanced rectal cancer; Total neoadjuvant therapy; Rectal cancer and preoperative induction therapy followed by dedicated operation; Long course chemoradiotherapy; Early surgical outcomes; Retrospective cohort study |
| Core Tip |
Rectal cancer and preoperative induction therapy followed by dedicated operation has emerged as a total neoadjuvant therapy strategy with improved oncological and functional outcomes. The impact of total neoadjuvant therapy on operative difficulty and short-term surgical outcomes compared to long course chemoradiotherapy remains an area of ongoing debate. This cohort study analyzed 99 cases and demonstrated that the rectal cancer and preoperative induction therapy followed by dedicated operation protocol does not increase surgical difficulty or compromise early surgical outcomes in comparison to long course chemoradiotherapy. It may also confer a shorter total stoma duration and lower permanent stoma rate. |
| Publish Date |
2025-11-14 00:56 |
| Citation |
Jabbar SAA, Choo ALE, Wong NW, Ngu JCY, Teo NZ. Comparing early surgical outcomes between total neoadjuvant therapy and standard long course chemoradiotherapy for rectal cancer. World J Gastrointest Oncol 2025; 17(11): 111250 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i11/111250.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i11.111250 |
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