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10/21/2025 9:08:30 AM | Browse: 3 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 111261
Country Croatia
Received
2025-06-26 12:40
Peer-Review Started
2025-06-26 12:40
To Make the First Decision
Return for Revision
2025-07-14 09:44
Revised
2025-07-25 18:24
Second Decision
2025-09-15 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-15 05:06
Articles in Press
2025-09-15 05:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-14 08:08
Publish the Manuscript Online
2025-10-21 09:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Clinical impact of multidrug-resistant organisms in liver cirrhosis: A retrospective cohort study in the intensive care setting
Manuscript Source Invited Manuscript
All Author List Iva Kosuta, Jaksa Babel, Viktor Domislovic, Frano Susak, Laura Peretin, Dijana Varda Brkic, Ivana Mareković, Radovan Radonic and Anna Mrzljak
ORCID
Author(s) ORCID Number
Iva Kosuta http://orcid.org/0000-0002-1342-8722
Jaksa Babel http://orcid.org/0000-0001-8405-2737
Viktor Domislovic http://orcid.org/0000-0002-3715-5730
Frano Susak http://orcid.org/0000-0002-3866-2814
Laura Peretin http://orcid.org/0009-0003-2386-2498
Dijana Varda Brkic http://orcid.org/0000-0001-5614-9486
Ivana Mareković http://orcid.org/0000-0002-3471-4285
Radovan Radonic http://orcid.org/0000-0002-3147-9160
Anna Mrzljak http://orcid.org/0000-0001-6270-2305
Funding Agency and Grant Number
Corresponding Author Iva Kosuta, Consultant, MD, PhD, Division of Intensive Care, Department of Internal Medicine, University Hospital Centre Zagreb, Ulica Mije Kišpatića 12, Zagreb 10000, Croatia. ivakosuta@gmail.com
Key Words Liver cirrhosis; Acute-on-chronic liver failure; Critical care; Multidrug-resistant organisms; Colonization; Infection
Core Tip This retrospective intensive care unit cohort study evaluated the impact of multidrug-resistant colonization in patients with liver cirrhosis. While colonization was common, especially in those with acute-on-chronic liver failure, it was not independently linked to infection or short-term mortality. However, high concordance between colonizing and infecting strains supports its role in guiding empirical antibiotic therapy once infection is suspected. These findings highlight the importance of early screening, local resistance data, and tailored empirical treatment to improve outcomes of critically ill patients with cirrhosis.
Publish Date 2025-10-21 09:08
Citation <p>Kosuta I, Babel J, Domislovic V, Susak F, Peretin L, Varda Brkic D, Mareković I, Radonic R, Mrzljak A. Clinical impact of multidrug-resistant organisms in liver cirrhosis: A retrospective cohort study in the intensive care setting. <i>World J Gastroenterol</i> 2025; 31(39): 111261</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i39/111261.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i39.111261
Full Article (PDF) WJG-31-111261-with-cover.pdf
STROBE Statement 111261-STROBE-statement.pdf
Manuscript File 111261_Auto_Edited_080556.docx
Answering Reviewers 111261-answering-reviewers.pdf
Audio Core Tip 111261-audio.mp4
Biostatistics Review Certificate 111261-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111261-conflict-of-interest-statement.pdf
Copyright License Agreement 111261-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111261-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111261-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111261-non-native-speakers.pdf
Supplementary Material 111261-supplementary-material.pdf
Peer-review Report 111261-peer-reviews.pdf
Scientific Misconduct Check 111261-scientific-misconduct-check.png
Scientific Editor Work List 111261-scientific-editor-work-list.pdf
CrossCheck Report 111261-crosscheck-report.pdf