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11/25/2025 11:05:33 AM | Browse: 4 | Download: 25
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 111285
Country Singapore
Received
2025-06-26 15:52
Peer-Review Started
2025-06-26 15:52
First Decision by Editorial Office Director
2025-07-11 10:16
Return for Revision
2025-07-12 19:18
Revised
2025-07-28 10:19
Publication Fee Transferred
Second Decision by Editor
2025-09-22 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-22 08:30
Articles in Press
2025-09-22 08:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-17 02:39
Publish the Manuscript Online
2025-11-25 11:05
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Minireviews
Article Title Evidence outside the box: Minimally invasive treatment for anal fistula
Manuscript Source Invited Manuscript
All Author List Kah Hau Luke Chua and Daniel Jin Keat Lee
ORCID
Author(s) ORCID Number
Kah Hau Luke Chua http://orcid.org/0009-0004-5881-360X
Daniel Jin Keat Lee http://orcid.org/0000-0002-0741-5386
Funding Agency and Grant Number
Corresponding Author Daniel Jin Keat Lee, FRCS (Ed), MD, Department of General Surgery, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore, Singapore 768828, Singapore. daniel.lee@geriatricsurgery.org.sg
Key Words Anal fistula management; Minimally invasive; Regenerative methods; Stem cells; Fistula plug; Matrix; Ligation of intersphincteric fistula tract; Fistula laser closure; Video-assisted anal fistula treatment; Over-the-scope clip
Core Tip We present a review summarising the most up-to-date insights into minimally invasive treatment for anal fistulae. Representing new frontiers in fistula treatment, these “sphincter-preserving” modalities seek to balance both recurrence prevention and continence preservation. The newest regenerative solutions, including autologous stem cell therapy and fistula plugs derived from extracellular and synthetic matrices, will be covered, as well as pertinent non-regenerative solutions like fistula laser closure, video-assisted anal fistula treatment, and over-the-scope clips. We consolidated and examined pertinent literature while weighing the pros and cons of each procedure.
Publish Date 2025-11-25 11:05
Citation

Chua KHL, Lee DJK. Evidence outside the box: Minimally invasive treatment for anal fistula. World J Gastrointest Surg 2025; 17(11): 111285

URL https://www.wjgnet.com/1948-9366/full/v17/i11/111285.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i11.111285
Full Article (PDF) WJGS-17-111285-with-cover.pdf
Manuscript File 111285_Auto_Edited_093520.docx
Answering Reviewers 111285-answering-reviewers.pdf
Audio Core Tip 111285-audio.m4a
Conflict-of-Interest Disclosure Form 111285-conflict-of-interest-statement.pdf
Copyright License Agreement 111285-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111285-non-native-speakers.pdf
Peer-review Report 111285-peer-reviews.pdf
Scientific Misconduct Check 111285-scientific-misconduct-check.png
Scientific Editor Work List 111285-scientific-editor-work-list.pdf
CrossCheck Report 111285-crosscheck-report.pdf