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9/19/2025 7:57:21 AM | Browse: 320 | Download: 50
Publication Name World Journal of Gastroenterology
Manuscript ID 111293
Country Japan
Received
2025-06-27 02:53
Peer-Review Started
2025-06-27 02:53
To Make the First Decision
Return for Revision
2025-07-15 10:31
Revised
2025-07-28 12:28
Second Decision
2025-08-21 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-21 06:26
Articles in Press
2025-08-21 06:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-11 06:44
Publish the Manuscript Online
2025-09-19 07:57
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Predicting pathological complete response to chemoradiotherapy using artificial intelligence-based magnetic resonance imaging radiomics in esophageal squamous cell carcinoma
Manuscript Source Invited Manuscript
All Author List Atsushi Hirata, Koichi Hayano, Toru Tochigi, Yoshihiro Kurata, Tadashi Shiraishi, Nobufumi Sekino, Akira Nakano, Yasunori Matsumoto, Takeshi Toyozumi, Masaya Uesato and Gaku Ohira
ORCID
Author(s) ORCID Number
Atsushi Hirata http://orcid.org/0000-0001-5931-7596
Koichi Hayano http://orcid.org/0000-0003-4733-8220
Akira Nakano http://orcid.org/0000-0002-2506-1825
Takeshi Toyozumi http://orcid.org/0000-0002-0939-3299
Masaya Uesato http://orcid.org/0000-0002-6766-5600
Gaku Ohira http://orcid.org/0000-0001-7246-5390
Funding Agency and Grant Number
Corresponding Author Koichi Hayano, FACS, MD, PhD, Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan. hayatin1973@yahoo.co.jp
Key Words Esophageal cancer; Diffusion weighted imaging; Chemoradiation therapy; Radiomics; Machine learning
Core Tip Accurately predicting pathological complete response (pCR) to chemoradiotherapy in esophageal squamous cell carcinoma remains a critical clinical challenge. This study introduces a novel artificial intelligence-based model leveraging radiomics features from pre-treatment diffusion-weighted magnetic resonance imaging. By integrating semi-automated three dimensions tumor segmentation with an automated machine learning framework, our model demonstrated high predictive accuracy for pCR (area under the curve = 0.85) and successfully stratified patients into distinct prognostic groups based on relapse-free survival. This non-invasive biomarker is a promising tool for constructing optimal treatment strategies, thereby advancing personalized medicine and significantly improving patient outcomes.
Publish Date 2025-09-19 07:57
Citation <p>Hirata A, Hayano K, Tochigi T, Kurata Y, Shiraishi T, Sekino N, Nakano A, Matsumoto Y, Toyozumi T, Uesato M, Ohira G. Predicting pathological complete response to chemoradiotherapy using artificial intelligence-based magnetic resonance imaging radiomics in esophageal squamous cell carcinoma. <i>World J Gastroenterol</i> 2025; 31(36): 111293</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i36/111293.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i36.111293
Full Article (PDF) WJG-31-111293-with-cover.pdf
Manuscript File 111293_Auto_Edited_031741.docx
Answering Reviewers 111293-answering-reviewers.pdf
Audio Core Tip 111293-audio.mp3
Biostatistics Review Certificate 111293-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111293-conflict-of-interest-statement.pdf
Copyright License Agreement 111293-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111293-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111293-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 111293-non-native-speakers.pdf
Peer-review Report 111293-peer-reviews.pdf
Scientific Misconduct Check 111293-scientific-misconduct-check.png
Scientific Editor Work List 111293-scientific-editor-work-list.pdf
CrossCheck Report 111293-crosscheck-report.pdf