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11/27/2025 7:53:57 AM | Browse: 9 | Download: 45
Publication Name World Journal of Hepatology
Manuscript ID 111354
Country Egypt
Received
2025-06-30 07:33
Peer-Review Started
2025-06-30 07:33
First Decision by Editorial Office Director
2025-07-11 10:19
Return for Revision
2025-07-13 11:33
Revised
2025-07-26 11:41
Publication Fee Transferred
Second Decision by Editor
2025-10-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-27 09:46
Articles in Press
2025-10-27 09:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-17 05:26
Publish the Manuscript Online
2025-11-27 07:53
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Artificial intelligence in metabolic dysfunction-associated steatotic liver disease: Machine learning for non-invasive diagnosis and risk stratification
Manuscript Source Invited Manuscript
All Author List Mona Abd-Elmonem Hegazy
ORCID
Author(s) ORCID Number
Mona Abd-Elmonem Hegazy http://orcid.org/0000-0001-9002-2868
Funding Agency and Grant Number
Corresponding Author Mona Abd-Elmonem Hegazy, Department of Internal Medicine, Kasr Aliny hospital, Faculty of Medicine, Cairo University, kasr Alainy Street, Garden City, Cairo 12556, Egypt. monahegazy@cu.edu.eg
Key Words Metabolic dysfunction-associated steatotic liver disease; Machine learning; Deep learning; Risk prediction; Disease stratification
Core Tip Artificial intelligence (AI), machine learning and deep learning, holds transformative potential for the non-invasive diagnosis and risk stratification of metabolic dysfunction-associated steatotic liver disease (MASLD). These AI models utilize readily available clinical data, biomarkers, and imaging modalities (ultrasound, computed tomography, magnetic resonance imaging) to detect steatosis, predict disease risk, and stage fibrosis with greater accuracy than conventional scoring systems such as fibrosis-4. Despite their promising performance, several challenges hinder widespread clinical adoption, including the need for data standardization, rigorous prospective validation, model interpretability, and seamless integration into existing healthcare workflows. Overcoming these barriers is essential to fully harness AI potential in improving MASLD diagnosis and management.
Publish Date 2025-11-27 07:53
Citation

Hegazy MAE. Artificial intelligence in metabolic dysfunction-associated steatotic liver disease: Machine learning for non-invasive diagnosis and risk stratification. World J Hepatol 2025; 17(11): 111354

URL https://www.wjgnet.com/1948-5182/full/v17/i11/111354.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i11.111354
Full Article (PDF) WJH-17-111354-with-cover.pdf
Manuscript File 111354_Auto_Edited_111241.docx
Answering Reviewers 111354-answering-reviewers.pdf
Audio Core Tip 111354-audio.m4a
Conflict-of-Interest Disclosure Form 111354-conflict-of-interest-statement.pdf
Copyright License Agreement 111354-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111354-non-native-speakers.pdf
Peer-review Report 111354-peer-reviews.pdf
Scientific Misconduct Check 111354-scientific-misconduct-check.png
Scientific Editor Work List 111354-scientific-editor-work-list.pdf
CrossCheck Report 111354-crosscheck-report.pdf