BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
12/25/2025 3:52:07 AM | Browse: 0 | Download: 0
 |
Received |
|
2025-07-01 01:10 |
|
Peer-Review Started |
|
2025-07-01 01:10 |
|
First Decision by Editorial Office Director |
|
2025-07-31 08:28 |
|
Return for Revision |
|
2025-07-31 08:28 |
|
Revised |
|
2025-08-03 15:40 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2025-11-04 00:02 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-11-11 10:26 |
|
Articles in Press |
|
2025-11-11 10:26 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-12-18 03:06 |
|
Publish the Manuscript Online |
|
2025-12-25 03:52 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Minireviews |
| Article Title |
Novel developments in retinal regeneration: Advances and future outlooks in stem cell therapy
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Zeppieri, Federico Visalli, Mutali Musa, Alessandro Avitabile, Rosa Giglio, Daniele Tognetto, Caterina Gagliano, Fabiana D’Esposito and Francesco Cappellani |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Marco Zeppieri, MD, PhD, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Stem cells; Induced pluripotent stem cells; Retinal degeneration; Retinal pigment epithelium; Regenerative medicine; Gene editing |
| Core Tip |
Stem cell therapies have a revolutionary potential to restore eyesight in individuals afflicted with retinal degenerative disorders, including age-related macular degeneration, retinitis pigmentosa, and Stargardt disease. Progress in human embryonic stem cell- and induced pluripotent stem cell-derived retinal cells, novel delivery mechanisms, and gene-editing methods is expediting clinical use. Nonetheless, enduring functional integration, immunological tolerance, and carcinogenic hazards persist as unresolved difficulties. Future success will rely on combinatorial strategies and global regulatory alignment to fully realize the potential of regenerative ophthalmology. |
| Publish Date |
2025-12-25 03:52 |
| Citation |
Zeppieri M, Visalli F, Musa M, Avitabile A, Giglio R, Tognetto D, Gagliano C, D’Esposito F, Cappellani F. Novel developments in retinal regeneration: Advances and future outlooks in stem cell therapy. World J Stem Cells 2025; 17(12): 111374 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i12/111374.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i12.111374 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
